The Impact of Intimal Tear Location and Partial False Lumen Thrombosis in Acute Type B Aortic Dissection

Partial false lumen (FL) thrombosis is a risk factor for long-term mortality in acute type B aortic dissection (ATBAD). This study investigates FL pressures in models of ATBAD with patent and partially thrombosed FL... ...A programmable pulsatile pump (SuperPump; ViVitro Systems, Victoria, BC, Canada) was connected to the left ventricle through a cannula inserted into the apex... ...In a biologic model of ATBAD, the number, location, and FL thrombosis status determine FL pressure. In the setting of partial FL thrombosis, the FL pressure is reduced with proximal tear occlusion and increased with distal tear occlusion. Reduced FL pressure is related to retrograde flow...

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