Pulse Duplicator

The ViVitro Pulse Duplicator system is the world’s most widely used in vitro cardiovascular hydrodynamic testing system.

It is composed of the ViVitro Model Left Heart, SuperPump and ViViTest data acquisition system. The components work together to assess the performance of prosthetic heart valves under simulated cardiac conditions.



Contact Us for a more comprehensive understanding of how the ViVitro Pulse Duplicator can be customized to expand and enhance your device testing capabilities.


Product Code: PD2010
  • Capable of testing a range of prosthetic heart valves including stented tissue, percutaneous, stentless, mechanical, and other valves
  • Flow and pressure readings can be collected and analyzed in real-time, meeting ISO 5840, ISO 5840-3, ISO-17845, and FDA requirements
  • Peripheral resistance and supplementary characteristic compliances to simulate cardiovascular character and resistance
  • Valves can be tested individually or simultaneously
  • Pressure readings from atrium, ventricle, and aorta
  • Flow can be measured directly at the aortic or mitral sites
  • Optically clear view ports permit ultrasound transmission for flow assessment
  • Allows hydrodynamic testing of heart valve replacements in order to assess mechanical and hemodynamic performance
  • Ventricle membrane to replicate the natural chamber flow
  • For testing other implantable cardiac devices, customizations, optional components, and accessories are available
Dry weight
25 lbs
32 x 18 x 20 inches
115V / 230VAC, 50-60Hz
Temperature range
up to 40°C ± 0.1°C
Flow rate
1 - 10 L/min
Heart rate
2 - 220 bpm

When coupled with the ViVitro Pulse Duplicator, ViViTest provides the most powerful, user-friendly tool for hydrodynamic testing.

The ViViTest control system inputs a waveform to the SuperPump while the data acquisition system captures and analyzes physiological pressures and valve flow rates.


Data Acquisition

  • Flow and pressure readings can be collected and analyzed in real time meeting ISO 5840, ISO 5840-3 and FDA requirements
  • Calibration wizards walk new users through the set up process, facilitating a wide array of data collection options.
  • Collects pressure and flow data for complete hydrodynamic performance.
  • Provides output files in versatile formats for easy analysis in Excel and MatLab


Waveform Control

  • Ability to create and control cardiac waveforms at various physiological states and frequencies, including arrhythmia and wave trains
  • Waveforms can be easily created with up to 1200 control statements
  • Backwards compatible with ViVitro products
  • .Net 3 Platform
  • Configured for 64-bit Windows 7 operating systems
  • Installer allows for easy updates
  • Singular program eliminates the need for intrusive third party software

ViVitest Data

Viscoelastic Impedance Adapter (VIA)

Product Code: VIA7991

The VIA consists of a unique combination of resistive and compliance elements to replicate the viscoelastic properties of the ventricle. It works with the SuperPump to produce realistic waveforms.

  • The dp/dt ratio can be adjusted to produce both physiological and diseased cardiac models
  • Filters high frequency noise when testing prosthetic valves and aortic roots
  • Easily adjusted


Fixed resistance
200 c.g.s. units
Compliance air volumes
SOURCE 0-120 ml, OUTPUT 0-60 ml, syringe adjustable
Total liquid volume
500 ml with SOURCE / OUTPUT compliance air volumes zero
VIA reduces the volume of fluid transmitted between the source and the load
Acrylic, Polycarbonate, Delrin, Nylon, Polyethylene, Stainless Steel, Viton

Heat Exchanger

Product Code: HE9991

The ViVitro heat exchanger is a highly efficient add-on to the ViVitro Pulse Duplicator. It allows the heating of test fluid with minimal interference of the fluid flow.

  • An isolated inflow and outflow metal heat conducting channel transfers heat to the solution
  • Maintains testing solution to desired temperature ± 0.5 °C.

Heat Bath Temperature Controller

Product Code: 5953N.A. , 5954Int'l

These heated circulating baths feature a long life, high-wattage heater that delivers rapid fluid heat-up, optimized for the ViVitro Pulse Duplicator

  • The over temperature and low reservoir level cutoffs eliminate risk of over heating system components


Reservoir volume
6 litres (1.5 gallons)
Temperature range
ambient 15°C to 150°C
Digital ±0.05°C
Work area dimensions
8 x 6 x 5¼ inches (20 x 15 x 13 cm)
Overall dimensions
9¼ x 14 x 14¾ inches (23 x 36 x 37 cm)
1000 W
Pumping capacity
12 L/min at 0 psig
Electrical requirements
115 VAC, 60 Hz, 15 amp or 230 VAC, 50 Hz 10 amps (specify when ordering)

Left Ventricle Outflow Tract (LVOT)

Product Code: 18903

The ViVitro model heart can be used to test prosthetic valves in compliant conduits to simulate left ventricular outflow tracts.

Available in the following sizes: 12, 14, 16, 18, 20, 22, 24, 26, 28, and 29 mm ID.

LVOT Assemblies

Percutaneous Heart Valve Entry Ports

The percutaneous entry components allow for catheter access and valve deployment into the Model Left Heart’s simulated aorta.

  • Two insertion ports available in standard French sizes (16 and 32)
  • Insertion of such devices can be done while the flow loop is operating under pressure
  • Custom sizes may be requested to ensure a proper fit

Digital Manometer

Product Code: 6104

This precision, handheld, digital pressure reference manometer allows for convenient calibration of pressure transducers.

  • Engineering Units - Inches of H2O (select 4 °C, 20 °C, or 60 °F), PSI, mm of Hg, inches of Hg, mBars, Bars, kPa, kg/cm2, cm of H2O and user selectable scaling.
  • Accuracy: ±0.05% FS or optional ±0.025% FS
  • Media Compatibility - DN: Non-isolated differential sensor for clean, dry, non-corrosive gases. GI & AI: Isolated Gauge or Absolute sensor for fluids compatible with 316L SS
  • Provided with three transducer manifold
  • The M2 series can be recalibrated in the field for zero, span, and linearity. The user has the option to select a 1 point or 5 point calibration procedure. Enables users with accurate primary standards to calibrate their devices locally if desired


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