The ViVitro Pulse Duplicator system is the world’s most widely used in vitro cardiovascular hydrodynamic testing system.
It is composed of the ViVitro Model Left Heart, SuperPump, Flow Measuring System and ViViTest data acquisition system. The components work together to assess the performance of prosthetic heart valves under simulated cardiac conditions.
The Pulse Duplicator System simulates the function of the heart by generating pulsatile flow through prosthetic heart valves placed in the Model Left Heart. The Pulse Duplicator simulates physiological or other complex flow variations while allowing the user to vary the peripheral resistance and compliance of the system. Pressure ports and flow measuring locations allow for data to be collected from aortic or mitral sites. Transparent viewpoints allow multiple viewing angles of the valve including inflow and outflow.
When the ViViTest software control system is combined with the ViVitro Labs Pulse Duplicator, physiological flow and pressure can be quickly, easily and reliably collected, and analyzed. The software also allows the user to easily modify and customize the waveforms the pump follows.
The ViVitro Pulse Duplicator System is used by the US Food and Drug Administration and is recognized by a number of other regulatory bodies worldwide including TÜV, BSI and the Chinese SFDA.
Contact Us for a more comprehensive understanding of how the ViVitro Pulse Duplicator can be customized to expand and enhance your device testing capabilities.
The ViVitro Model Left Heart includes transparent parts to visualize valve function and adjacent flow fields. Ports are available for transducers to measure wall pressures in the left atrium, left ventricle, aortic outflow tract and downstream of the aortic valve.
When coupled with the ViVitro Pulse Duplicator, ViViTest provides the most powerful, user-friendly tool for hydrodynamic testing.
The Viscoelastic Impedance Adapter (VIA) works in conjunction with the SuperPump to produce more physiological ventricular pressures. It consists of a fixed resistive element and two adjustable compliance chambers, that simulate ventricular viscoelastic behavior.
The ViVitro Labs Function Tester is an accessory to the ViVitro Labs Pulse Duplicator and intended for Production / QC applications. It provides a simplified system that assesses valve performance criteria for production quality control.
Configured as a turnkey solution, it captures fast, reliable results for a fraction of the cost of designing an in-house system.
The Function Tester, in conjunction with QCTest software, assesses pressure and flow criteria while recording high speed valve footage via an integrated camera.
The ViVitro Labs Function Tester system includes a quick-change valve holder that is can be customized to specific valve geometry.
The ViVitro heat exchanger is a highly efficient add-on to the ViVitro Pulse Duplicator. It allows the heating of test fluid with minimal interference of the fluid flow.
These heated circulating baths feature a long life, high-wattage heater that delivers rapid fluid heat-up, optimized for the ViVitro Pulse Duplicator
The ViVitro Aortic Conduit Mount (formerly LVOT) can be used to mount a compliant aorta and test percutaneous valves in the ViVitro Model Left Heart system. A variety of Aortic Conduit Mount sizes can be custom made to accommodate silicone tubes with relaxed tube IDs of 12-29 mm. A tube may be expandable up to about 50mm OD.
Available in the following sizes: 12, 14, 16, 18, 20, 22, 24, 26, 28, and 29 mm ID.
The Large Atrium chamber allows devices with an outer diameter of up to 55mm to be tested in the Pulse Duplicator.
• Expands the mitral device testing capabilities of the system
• Easily added to a ViVitro Labs Pulse Duplicator
• Quick-release system allows fast device changes
ViVitro can provide two methods of deploying devices into the Pulse Duplicator; either Transfemoral or Transapical access. The Percutaneous Access Device is designed to accommodate up to 26 French deployment devices and mounts easily to a ViVitro Model Left Heart. Insertion of such devices can be done while the flow loop is operating under pressure.
This precision, handheld, digital pressure reference manometer allows for convenient calibration of pressure transducers.
The digital thermometer allows for easy fluid temperature measurement in the Pulse Duplicator.