Articles Related to Pulse Duplicator

Guangyu Zhu; Masakazu Nakao; Qi Yuan and Joon Hock Yeo Proceedings of the 10th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 1: BIODEVICES, 186-189, 2017, Porto, Portugal

Truly stentless polymeric valve prosthesis can be a viable alternative for aortic valve replacement (AVR). In the present paper, the dynamic and hemodynamic performance of a novel designed expanded-polytetrafluoroethylene (ePTFE) stentless tri-leaflet valve was assessed experimentally.... ... The in-vitro tests were performed under time-varying physiological pressure by using the Vivitro pulse duplicator. ... The Vivitro pulse duplicator (Vivitro Systems Inc., Victoria, BC, Canada) was used to generate the physiological pressure and flow in the left ventricle and aorta. ...

Other Products Cited:  Pulsatile Flow Simulation

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M. Alizadeh, M. Cote, and A Branzan Albu P Sharma, FM Bianchi - Image Analysis 20th Scandinavian Conference, SCIA 2017,

...The valve orifi ce area over time, which informs on the opening and closing motion patterns, constitutes a key quality metric for PHV assessment... ...In this paper, we propose a novel orifi ce segmentation approach for automatic prosthetic heart valves quantitative performance analysis, based on the detection of the leaflet free edges to accurately extract the actual orifi ce area.

Other Products Cited:  Flow Visualization

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Ng, Daniel Wai Hung. Neo, Si Yang. Ng, Chung Liu. Wong, Benedict Jun Shuan. Singapore Polytechnic School of Mechanical & Aeronautical Engineering

...Mechanical valves usually made from metal and fabrics are very durable but they have poor hemodynamic and are thrombogenic requiring permanent anticoagulation. Tissue heart valves constructed from biological tissues have excellent hemodynamic blood flow, but they lack durability. The project proposed a new valve design that is similar to a stentless tissue valve but made from a synthetic material, Polytetrafluoroethylene (PTFE)... The scope of this project includes designing a fixture to accommodate the valves in the ViVitro System and studying hemodynamic parameters such as pressure drop, flow rate, and dynamic leaflet behaviour of the valves. ...

Other Products Cited:  Heart Valve Testing

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Andrew K. Capullia, Maximillian Y. Emmerta, b, c, Francesco S. Pasqualinia, b, Debora Kehlb, Etem Caliskanb, c, Johan U. Linda, Sean P. Sheehya, Sung Jin Parka, Seungkuk Ahna, Benedikt Webera, b, Josue A. Gossa, Simon P. Hoerstrupa, b, Kevin Kit Parkera; Biomaterials Volume 133, July 2017, Pages 229–241

Tissue engineered scaffolds have emerged as a promising solution for heart valve replacement because of their potential for regeneration. However, traditional heart valve tissue engineering has relied on resource-intensive, cell-based manufacturing, which increases cost and hinders clinical translation. ...We demonstrated controlled modulation of these scaffold parameters and show initial biocompatibility and functionality in vitro...

Other Products Cited:  Tissue Engineering

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Bozkurt, S., Preston-Maher, G.L., Torii, R. et al. Ann Biomed Eng (2017). doi:10.1007/s10439-017-1828-2 First Online: 03 April 2017

Mitral regurgitation is a common mitral valve dysfunction which may lead to heart failure. This paper presents the design, development and hydrodynamic assessment of a novel bi-leaflet mitral valve suitable for transcatheter implantation. ... animal models. Hydrodynamic Tests. The hydrodynamic performances of the three valve prototypes were assessed on a hydro-mechanical cardiovascular pulse duplicator system (ViVitro Superpump SP3891, ViVitro, BC) (Fig. 3 ...

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Wentao Feng, Xianda Yang, Yang Liu, Yubo Fan Artificial Organs, 24 February 2017

Clinically, the percutaneous transcatheter aortic valve (TAV) has been reported to be deformed in a noncircular configuration after its implant. The deformation is universal and various, and it leads to serious leakage and durability problems. ...the present study investigated the effects of the aortic annulus deformation and the leaflet tissue thickness on the hydrodynamics of the TAV. ... Hydrodynamic testing. The TAVs were tested in a quasi-physiological artery pulsatile flow duplicator system, which was custom remoulded to adapt the testing of deformed TAV from commercially available pulse duplicator (Pulse Duplicator; Vivitro Labs, Victoria, BC, Canada.). ...

Other Products Cited:  Heart Valve Testing

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Sharan Ramaswamy, Makensley Lordeus, Omkar V. Mankame, Lilliam Valdes-Cruz, Steven Bibevski, Sarah M. Bell, Ivan Baez, Frank Scholl: Cardiovasc Eng Tech (2016).

...Assess the functional effectiveness of tri-leaflet PSIS bioscaffolds in the aortic position compared to standard tri-leaflet porcine bioprosthetic valves... ... (b) Pulse duplicator system (Vivitro Laboratories) used for the hydrodynamic evaluation of the valves. ... System calibration, pump control, data collection and analysis are all computer-controlled via software (Vivitest, Vivitro Labs). ...

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Claudio Capelli, Chiara Corsini, Dario Biscarini, Francesco Ruffini, Francesco Migliavacca, Alfred Kocher, Guenther Laufer, Andrew M. Taylor, Silvia Schievano, Martin Andreas, Gaetano Burriesci, Claus Rath: Cardiovascular Engineering and Technology (2016). doi:10.1007/s13239-016-0284-8

...Recently, novel bioprostheses which include a stent-based anchoring system have been introduced to allow rapid implantation, therefore reducing the duration and invasiveness of the intervention. ...The results showed how the performance of cardiac valve substitutes is negatively affected by the presence of pledget-armed sutures... ...The measurements were collected during ten cardiac cycles and analysed in the VSI software pack- age (VSI, ViVitro, Victoria, BC, Canada). The leaflets kinematics were visualised using a high-speed camera. For ...

Other Products Cited:  Software

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Onur Dur, Keif Fitzgerald, Paul Muller, Chris Parker Thoratec Corporation, Sunnyvale, CA company slide

The HeartMate PHP is a 13F catheter-based trans-aortic heart pump with a collapsible distal portion that expands to 24F to provide minimally invasive acute hemodynamic stabilization and left ventricular unloading in both prophylactic and emergent clinical settings... Objective: To evaluate the interaction of the HeartMate PHP with native cardiovascular system via in vitro pulsatile mock flow loop testing. A custom-built pulsatile heart simulator adapted from Vivitro Pulse Duplicator (Vivitro Labs Inc., Canada) was tuned to generate physiological flow pressure waveforms while mimicking the preload sensitivity of the native heart.

Other Products Cited:  Pulsatile Flow Simulation  VAD Testing

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Cole Feagler, Zeeshan Syedain and Robert Tranquillo University of Minnesota College of Science and Engineering Poster Report

While most commercial valves today use chemically-fixed porcine tissue in the construction of the replacement valves, the Tranquillo group has been exploring the use of decellularized, engineered tissue as leaflet material... ...The goal of this project was to engineer a commissure design to mitigate valve failure through tissue tearing, and to improve overall valve hemodynamics. (I.e. reduction of PVL)... ...Prototype TEHVs were tested to failure using a ViVitro Labs pulse duplicator, running custom LabView data acquisition software...

Other Products Cited:  Pulsatile Flow Simulation  Tissue Engineering

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