Cited Publications

A Novel Aortic Regurgitation Model from Cusp Prolapse with Hemodynamic Validation Using an Ex Vivo Left Heart Simulator

To simulate Aortic Regurgitation (AR), four porcine aortic valves were explanted, and the commissure between the two largest leaflets was detached and re-implanted 5 mm lower to induce cusp prolapse. … 1c), which has been previously described in detail [17, 18]. In brief, the simulator encompasses a programmable pulsatile linear piston pump (ViVitro Superpump, ViVitro Labs, Victoria, BC, Canada) that is attached to a custom left ventricular chamber …