Bicuspid aortic valve (BAV) is the most common congenital cardiac malformation, which had been treated off-label by transcatheter aortic valve replacement (TAVR) procedure for several years, until its recent approval by the Food and Drug Administration (FDA) and Conformité Européenne (CE) to treat BAVs.
...Materials and Methods Patient-specific in silico models and 3D printed replicas of 3
BAV patients with different degrees of post-TAVR paravalvular leakage (PVL) were
created. Patient-specific TAVR device deployment was modeled in silico and in vitro—following …
...PVL degree and locations were consistent with the clinical data. Cross-validation comparing the stent deformation and the flow parameters between the in silico and the in vitro models demonstrated good agreement....
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