Effect of aortic annulus size and prosthesis oversizing on the hemodynamics and leaflet bending stress of transcatheter valves: an in vitro study

There is few data about the patient- and prosthesis- related factors influencing the hemodynamics of transcatheter heart valves (THVs). The objective of this in vitro study was to assess the effect of aortic annulus size and prosthesis oversizing on the valve hemodynamics and estimated leaflet bending stress of the SAPIEN balloon-expandable THV. ... THV). Methods. In Vitro Model. For the purpose of this study, a left heart duplicator system was used (ViVitro Labs. Inc, BC, Canada). This simulator is capable of reproducing physiological pressure and flow waveforms. Briefly ...