Finding the ideal biomaterial for aortic valve repair with ex vivo porcine left heart simulator and finite element modeling

ABSTRACT Aortic valve (AV) repair (AVr) has become an attractive alternative to AV replacement for the correction of aortic insufficiency; however, little clinical evidence exists in determining which biomaterial at AVr would be optimal. Cusp replacement in AVr has... All aortic roots were connected to the ViVitro Left Heart Simulator (LHS; ViVitro Systems, Inc, Victoria, British Columbia, Canada) for baseline valve measurements acting as paired controls...