Influence of TAVR-dilatation concepts on hydrodynamic properties under pulsatile flow

The ViVitro Labs Pulse Duplicator is used in its standard configuration to assess the hydrodynamic performance of Transcatheter aortic valve prosthesis (TAVI) according to ISO 5840-3:2021 requirements (TAVR). "For the pulsatile flow testing a commercial pulse duplicator system (ViVitro Labs, Inc., Victoria, BC, Canada) was used. Testing was conducted at a heart rate of 70 bpm and a systolic duration of 35% ± 3%. The test fluid was 0.9% saline at a temperature of 37 °C ± 2°C. The cardiac output (CO) was varied between 2.0 l/min, 3.5 l/min, 5 l/min, and 7 l/min. And the mean aortic pressure (MAP) was adjusted to 100 mmHg ±5 mmHg in every measurement"