Transvalvular pressure gradients for different methods of mitral valve repair: only neochordoplasty achieves native valve gradients

Many surgical and interventional methods are available to restore patency for patients with degenerative severe mitral valve regurgitation... ...Eight porcine mitral valves were tested under pulsatile flow conditions in an in vitro pulsatile flow loop for haemodynamic quantification.... ...All surgical reconstruction techniques were able to sufficiently correct the acute mitral valve regurgitation.... ...The LV chamber was actuated using a computer-controlled piston pump (ViVitro Systems Inc., Victoria, Canada) attached to the LV chamber...