In Vitro Pulsatile Performance Evaluation of the HeartMate PHP TM (Percutaneous Heart Pump)

The HeartMate PHP is a 13F catheter-based trans-aortic heart pump with a collapsible distal portion that expands to 24F to provide minimally invasive acute hemodynamic stabilization and left ventricular unloading in both prophylactic and emergent clinical settings... Objective: To evaluate the interaction of the HeartMate PHP with native cardiovascular system via in vitro pulsatile mock flow loop testing. A custom-built pulsatile heart simulator adapted from Vivitro Pulse Duplicator (Vivitro Labs Inc., Canada) was tuned to generate physiological flow pressure waveforms while mimicking the preload sensitivity of the native heart.