Simulated use
testing & training

The ViVitro Endovascular Simulator creates physiological pulsatile flow and pressures for testing many types of cardiovascular devices and can be used for any portion of the cardiovascular system.

Our vascular flow platform brings physiological pulsatility to anatomical models for research and development. The simulator can easily be reconfigured for bench top, cath lab or portable cart installation.

The Endovascular Simulator addresses requirements of ISO 5840, ISO 25539, and ISO 7198 standards as they include simulated use guidelines.

Control a live cardiac flow in a standalone configuration. Using the ViVitro SuperPump pulsatile pump, the simulator’s programmable waveform system delivers physiological pulsatile flow. Test a variety of endovascular medical devices and delivery systems by adding anatomical models, including abnormalities or custom patient-specific models.

Simulated-use testing

Use the simulator to demonstrate that devices can be delivered and deployed in a safe, consistent and accurate manner within the intended implant site and with intended use conditions.

The ViVitro Endovascular Simulator is cited in numerous research studies throughout the world.   Visit our Citation Database for the current list of applications and articles.

Contact us to learn how the ViVitro Labs Endovascular Simulator can facilitate your device testing challenges.


Product Code: Tray 30543 // Compliance 25654

The Endovascular Simulator provides functional design testing for:

  • Pulsatile flow interactions
  • Deployment accuracy
  • Sizing
  • Conformability
  • Trackability and pushability
  • Torquability




The Endovascular Simulator provides functional design testing for:

  • Pulsatile flow interactions
  • Positioning
  • Deployment accuracy
  • Sizing
  • Conformability
  • Trackability and pushability
  • Torquability

Designed for Easy Adaptability

The simulator’s tray is a modular platform that accommodates anatomical models for a variety of transcatheter or surgical vascular interventions. It is easily reconfigured for different model sizes and connection types.

Aorta Model with Femoral Access


Lower Leg Arterial Model


Neuro Aneurysm Model


A compliance assembly provides adjustable air volume to allow system tuning for a wide range of pressure conditions.

Set-up is straightforward and simple

Inlet and outlet ports can be swapped out for the optional manifold for joining the return flow paths.

Inlet/Outlet Port


Optional manifold for joining return flow paths


Red lines indicate inlets, and outlet/return flow


A digital camera captures high resolution imagery of positioning and deployment. It can also be used to simulate fluoroscopy without the use of an expensive cath lab.


Capture high resolution video


Simulate fluoroscopy

Optional Components

The ViVitro Endovascular Simulator shares many other ViVitro product elements. This provides a low cost upgrade path, re-use of common parts, and ease of use.

Viscoelastic Impedance Adapter (VIA)

Product Code: VIA7991

A Viscoelastic Impedance Adaptor provides input waveform compliance to create physiological pressures and flows.

  • Adjustable dP/dt ratio to produce both physiological and diseased cardiac models
  • Filters high frequency noise when testing prosthetic valves and aortic conduits
  • Easily adjusted
Fixed resistance
200 c.g.s. units
Compliance air volumes
SOURCE 0-120 ml, OUTPUT 0-60 ml, syringe adjustable
Total liquid volume
500 ml with SOURCE / OUTPUT compliance air volumes zero
Acrylic, Polycarbonate, Delrin, Nylon, Polyethylene, Stainless Steel, Viton

Ex Vivo Simulator

Product Codes: 29348: Ex Vivo System Bundle / 10647: SuperPump System / 25654: Compliance Assembly 30146: Accessories / 30543: Tray Assembly

The Ex Vivo Simulator uses a ViVitro Labs SuperPump pulsatile pump to generate physiological flows in an excised heart for bench top testing. The system can model either the left or right heart, or two systems can be combined to generate a four chamber model.

  • The Ex Vivo beating heart combines clinical anatomical similarity with controllable physiological flow and pressure signatures for bench top testing. This results in repeatability and ease of use, and anatomical and functional performance previously only found in animal models.
  • Access sites at the arteries, atrium and apex allow for the insertion of catheters and other devices. Optional pressure transducers and data acquisition system acquire the arterial, ventricular and atrial pressures and a flow meter measures the cardiac output of the simulator.
  • Investigate valve movement with an endoscope or ultrasound. Pathological states such as low ejection fractions and high beat rates can be simulated with the heart via the SuperPump pulsatile pump. Degenerative and functional mitral regurgitation can be simulated by severing the mitral chords and pressurizing the left ventricle, respectively.

Heat Exchanger

Heat Exchanger Product Code: HE9991

The ViVitro Heat Exchanger allows heating of test fluid with minimal interference of the fluid flow.

  • An isolated inflow and outflow metal heat conducting channel transfers heat to the solution
  • Maintains testing solution to desired temperature ± 0.5°C

Heat Bath

Heat Bath Product Code: 10679 N.A., 10680 Int'l

The Heat Bath Temperature Controller delivers rapid fluid heat-up, optimized for the ViVitro Endovascular Simulator and Pulse Duplicator. These heated circulating baths feature a long life, high-wattage heater.

  • Over Temperature and Low Reservoir level automatic system cut-offs eliminate risk of over heating system components
Reservoir volume
6 litres (1.5 gallons)
Temperature range
ambient 15°C to 150°C
Digital ±0.05°C
Work area dimensions
20 x 15 x 13 cm
Overall dimensions
23 x 36 x 37 cm
1000 W
Pumping capacity
12 L/min at 0 psig
Electrical Requirements
115 VAC, 60 Hz, 15 amp or 230 VAC, 50 Hz 10 amps (specify when ordering)

Interchangeable Components

SuperPump pulsatile pump

The most widely used computer-controlled pump for cardiac flows. The ViVitro SuperPump pulsatile pump that powers the Endovascular Simulator is also the foundation for ViVitro’s Pulse Duplicator and Real Time Wear Tester. The SuperPump pulsatile pump can be operated independently with any type of cardiac flow loop. The SuperPump pulsatile pump provides pulsatile flow from 3 to 200 Beats per Minute and up to 15 Litres per Minute output. A Pump Head facilitates circulatory flow using two valves.  
Product Code: 10647
Tray Size:
612mm x 270mm x 53mm (Inside Dimensions - L x W x D)
# of Access Ports (Sides):
# of Access Ports (Ends):
Access Port Spacing (Sides):
Access Port Spacing (Ends):
Barbed Connector Sizes:
3/16”, ¼”, 5/16”, 3/8”, ½”, 5/8”, 1”
Max. Catheter Access Size:
26 French (standard)
34 French (optional)
# Pressure Channels (w/DAS):
# Flow Channels (w/DAS):
Camera Resolution:
1280 x 1024 (1.31MP)
Camera Frame Rate:
60 fps
The Endovascular Simulator is compatible with the following ViVitro products:
  • SuperPump pulsatile pump and Controller
  • Viscoelastic Impedance Adapter
  • Pump Head
  • Flow Measuring System
  • ViVitest Data Acquisition System
  • Heat Bath and Heat Exchanger
  • Pressure Transducers
  • Digital Thermometer

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