Experimental Flow Field Assessment – Digital Particle Image Velocimetry (DPIV)

Using Digital Particle Image Velocimetry (DPIV),  pulsatile flow conditions in the immediate vicinity of the device can be analyzed to determine the viability of cardiovascular devices meeting regulatory standards. Triggers for disease (such as shear stresses and regions of stagnation) can be quantified with a high degree of accuracy. Advanced methods, including proper orthogonal decomposition, also capture the implicit fluid mechanical phenomenon of interest.

Test Procedure

ViVitro Labs testing provides 2D high-speed information regarding the Quantitative and Qualitative nature of the flow surrounding a device. Qualitative outputs include flow assessment based on particle streaks with assessment and description of any occurrences of flow separation, flow stasis, vortex formation, jet nature, regurgitant and other fluid mechanical phenomenon. Quantitative outputs include velocity, shear stresses, and particle residence times during various phases of the cardiac cycle. Stagnant flow may induce potential blood clot formation during heart valve operation.

High flow velocities in the vicinity of the device may induce potential haemolysis and platelet activation.

 

Measured Parameters

  • Velocity
  • Shear stress (viscous shear stress, Reynolds shear stress)
  • Regions of stagnation
  • Qualitative analysis: Turbulent flow region, flow separation, vortex formation, jets
  • Calculated particle residence time (if required)

Scope

  • Transcatheter valves; TAVI, TMVR
  • Biological, Polymeric, Mechanical valves: Rigid or soft
  • Venous valves and conduits
  • Valvular conduits
  • Vena Cava Filters
  • Assist ventricular devices
  • Any device implant in flow models

Service Levels

Applicable Standards

  • ISO 5840-2:2021
    Cardiovascular implants — Cardiac valve prostheses — Part 2: Surgically implanted heart valve substitutes

  • ISO 5840-3:2021
    Cardiovascular implants — Cardiac valve prostheses — Part 3: Heart valve substitutes implanted by transcatheter techniques

Related Tests

OLE0914

Digital Particle Image Velocimetry (DPIV)- Flow Visualization Digital Particle Image Velocimetry (DPIV)- Flow Visualization Animation

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