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Suchitra Konduri, Yun Xing, James N. Warnock, Zhaoming He and Ajit P. Yoganathan; Annals of Biomedical Engineering: 33, Issue 9; 1158-1166; 2005.

Quantifying mitral regurgitation is difficult because of the complexity of the flow, geometry and motion of the mitral valve. In this paper a MRI compatible phantom was built incorporating a left ventricle and mitral valve motion. Valve motion was obtained using a pneumatic piston. The mitral valve was made regurgitant and the regurgitant volume quantified using a modified control volume method. The modification to the method was the addition of mitral motion correction. T

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David Paniagua, MD, José A. Condado, MD, José Besso, MD, Manuel Vélez, MD, Bruno Burger, MD, Salvatore Bibbo, MD, Douglas Cedeno, MD, Harry Acquatella, MD, Carlos Mejia, BA, Eduardo Induni, MD, and R. David Fish, MD; Texas Heart Institute Journal: 32, Issue 3; 393–398; 2005.

The transcatheter route is an emerging approach to treating valvular disease in high-risk patients. The 1st clinical antegrade transcatheter placement of an aortic valve prosthesis was reported in 2002. We describe the first retrograde transcatheter implantation of a new aortic valve prosthesis, in a 62-year-old man with inoperable calcific aortic stenosis and multiple severe comorbidities.

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R. K. Kaminsky; H. J. Weber; A. P. Simons; S. Kallweit; K. Kramm; P. R. Verdonck; Computer Methods in Biomechanics and Biomedical Engineering: 8, Issue 4; 159 – 160; 2005.

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Carsten J. Bellera, Michel R. Labrosseb, Francis Robicsek and Mano J. Thubrikar; Interactive Cardiovascular and Thoracic Surgery: 5; 526-530; 2006.

Our goal was to understand why it is difficult to achieve reliable valve competence after aortic valve-sparing surgery, and to propose quantitative data aimed at improving the outcome of the procedure. Valve-sparing procedures were performed in patients with dilated aortic roots and aortic regurgitation, and reproduced in physical models to explore what should be the restored dimensions of the aortic root and leaflets for valve sparing to be successful.

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Ashwin Prakash, MD, Ruchira Garg, MD, Edward N. Marcus, MSc, Glenn Reynolds, PhD, Tal Geva, MD, Andrew J. Powell, MD; Journal of Magnetic Resonance Imaging: 24, Issue 3; 676 – 682; 2006.

To test the agreement between conventional and sensitivity-encoded (SENSE) velocity encoded cine (VEC) MRI in a flow phantom and in subjects with congenital and acquired heart disease...

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Zhang, Pei; Yeo, Joon Hock; Hwang, N H. C.; ASAIO Journal: 52, Issue 4; 391-397; 2006.

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Kheradvar, Arash; Kasalko, Jeff; Johnson, Derrick; Gharib, Morteza; ASAIO Journal: 52, Issue 1; 34-38; 2006.

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Arash Kheradvar and Morteza Gharib; Annals of Biomedical Engineering: 35, Issue 12; 2050-2064; 2007.

Several studies have suggested that the mitral annulus displacement and velocity in early diastole can be used as indicators of diastolic performance.

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Kheradvar, Arash; Milano, Michele; Gharib, Morteza; ASAIO Journal: 53, Issue 1; 8-16; 2007.

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Julia Mascherbauer, Christina Fuchs, Martin Stoiber, Heinrich Schima, Elisabeth Pernicka, Gerald Maurer and Helmut Baumgartner; European Heart Journal: 29, Issue 16; 2049-2057; 2008.

Hypertension is a frequent finding in patients with aortic stenosis (AS). However, controversial data about the influence of systemic blood pressure on the quantification of AS have been published.

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A. A. Sakhaeimanesh; Journal of Medical Engineering & Technology: 32, Issue 6; 434 – 439; 2008.

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Mazur, Daniel E.; Osterholzer, Kathryn R.; Toomasian, John M.; Merz, Scott I.; ASAIO Journal: 54, Issue 5; 523-528; 2008.

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Arash Kheradvar and Morteza Gharib; Annals of Biomedical Engineering: 37, Issue 1; 2009.

In the field of cardiology, the current ability to accurately detect diastolic dysfunction is unsatisfactory due to the lack of an effective diagnostic index. Isolated indexes obtained from echocardiography are all restricted to a certain aspect of ventricular diastolic function only, and individually cannot be regarded...

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Ali N. Azadani, PhD, Nicolas Jaussaud, MD, Peter B. Matthews, BS, Liang Ge, PhD, T. Sloane Guy, MD, Timothy A.M. Chuter, MD, Elaine E. Tseng, MD.; Ann Thorac Surg 2009;88:1857-1863, Aug 11, 2009.

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Travis BR, Fowler BL, Robicsek F.; J Heart Valve Dis. (5):499-506; Sep 18, 2009.

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Thomas E. Claiborne, Danny Bluestein, Richard T. Schoephoerster, The International Journal of Artificial Organs, Vol. 32, no. 5, pp. 262-271; 2009.

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Jeffrey J. Heys, Nicole Holyoak, Anna M. Calleja, Marek Belohlavek and Hari P. Chaliki, The Open Biomedical Engineering Journal 4, 123-128; 2010.

The assessment of the severity of aortic valve stenosis is done by either invasive catheterization or non-invasive Doppler Echocardiography in conjunction with the simplified Bernoulli equation. The catheter measurement is generally considered more accurate, but the procedure is also more likely to have dangerous complications.

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Mathias Vermeulen, Cedric Van Holsbeke, Tom Claessens, Jan W. De Backer, Peter Van Ransbeeck, Pascal Verdonck, 15th Int Symp on Applications of Laser Techniques to Fluid Mechanics Lisbon, Portugal, 05-08 July, 2010

ABSTRACT The objective of this study is to analyze the flow pattern trough a patient specific lower airway under multiple breathing conditions. The measured Particle Image Velocimetry (PIV) results are quantitatively and quantitatively compared ...

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Michel R. Labrosse, Keegan Lobo, Carsten J. Beller, Journal of Biomechanics 43, 1916–1922; 2010.

A novel finite element model of the natural aortic valve was developed implementing anisotropic hyperelastic material properties for the leaflets and aortic tissues, and starting from the unpressurized geometry. Static pressurization of the aortic root, silicone rubber moulds and published data helped to establish the model parameters, while high-speed video recording of the leaflet motion in a left-heart simulator allowed for comparisons with simulations.

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Andrew D. Michaels MD, David Mester, Catheterization and Cardiovascular Interventions Vol. 77, issue 5, pages 726-732, April 2011.

Abstract
OBJECTIVES:
Accurate assessment of prosthetic mechanical valve malfunction is challenging for non-invasive and invasive techniques. We evaluated a 0.014-inch pressure-sensing coronary guidewire to assess mechanical valve dysfunction.

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