Articles Related to Applications

João Gomes-Fonseca ; Pedro Morais ; Sandro Queirós ; Fernando Veloso ; António C. M. Pinho ; Jaime C. Fonseca ; Jorge Coreia-Pinto ; João L. Vilaça - 2018 IEEE 6th International Conference on Serious Games and Applications for Health (SeGAH)

This work aims to create a dynamic, ultrasound-compatible, realistic and flexible phantom of the left and right ventricles, with application in the diagnosis, planning, treatment and training in the cardiovascular field for studies using echocardiography. … the real tissues. Then, a commercial available computed-controlled dynamic piston pump (Vivitro Labs, Victoria, British Columbia, Canada) was used to pump water... into the model and consequently deform it. This pump system

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P Yu Electronic Theses & Dissertations (ETDs) (2011-) [3339] 2018

...This study focuses on investigating the hemodynamics inside an aneurysm for different inflow conditions and varying geometrical shapes. ... … precisely controlled. Re and α were varied between 50-250 and 2-5, respectively. A ViVitro Labs pump system was used to pump the fluid and Particle Image Velocimetry (PIV) was used to perform velocity measurements. The flow …

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R Kotzé, L Deorsola - 2018 Design of Medical Devices Conference, 2018

Mitral subvalvular apparatus plays an important role in mitral and ventricular dynamics by preserving annuloventricular continuity, known to be fundamental for ventricular function... ...We address these issues through the design of a novel semistented and chorded mitral valve that better mimics the native mitral annulus, leaflets and chordae function and can be made from off-the-shelf biomaterials with the potential to be implanted percutaneously... … Pulse duplicator setup We performed hydrodynamic testing in the mitral position on a hydro-mechanical pulse duplicator system (Vivitro Superpump System SP3891, Vivitro, Victoria, BC, Canada), described elsewhere [4]. We used a 25mm Sorin Bicarbon bileaflet …

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Deepa SritharanParinaz FathiJason D. WeaverStephen M. RettaChangfu WuNandini Duraiswamy - Cardiovascular Engineering and Technology pp 1–14

After implantation of a transcatheter bioprosthetic heart valve its original circular circumference may become distorted, which can lead to changes in leaflet coaptation and leaflets that are stretched or sagging.... … Valve hydrodynamic performance data were collected using a commercially available left heart Pulse Duplicator (Vivitro Systems) at 0, 41, 80, and 123 M cycles; at these intervals, the valves mounted in the metallic adapter …

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K Davis, JH Muller, CJ Meyer, FE Smit - (SAIBMEC), 2018 3rd Biennial South African, 2018

...The air volume shifts the pressure and flow rate waveforms in time and impact the physical operating conditions of the valves with constant input settings in the ViVitest software... … Results obtained from current pulse duplicators are subject to the setup and physical testing settings. The ViVitro Pulse Duplicator from ViVitroLabs Inc … Three different valves were tested in a ViVitro pulse duplicator where...

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Wei-Ling ChenChiu-Chin WuChung-Dann Kan - World Congress on Medical Physics and Biomedical Engineering 2018 pp 519-524

...Percutaneous pulmonary valve implantation (PPVI) has evolved as most exciting development surgical strategy with dysfunctional right ventricle-pulmonary artery conduits. ... ...The purpose of this study is to investigate the hemodynamic and functional consequences of the new design using a mock circulation system... … vasculature. Blood pressures and flows are driven by a digitally controlled hydraulic piston pump (ViViTro Labs Inc., Super Pump System, Victor, BC) to produce pulsatile waves with heart rates of 60 and 80 beats/min from ARV to ARA …

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Wei-Ling Chena, Chia-Hung Linb, Jieh-Neng Wangc, Pong-Jeu Lud, Ming-Yao Chand, Jui-Te Wue, Chung-Dann Kanf

...This study proposes an assistive technology to quantify regurgitation using the regurgitation fraction (RF) and heart pump efficiency (HPE). … pulmonary valves. The blood pressure and flow were driven by a digitally controlled hydraulic piston pump (ViViTro Labs Inc., Super Pump System, Victor, BC) to produce pulsatile waves with heart rates of 60 and 80 beats/min. The …

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J Sathananthan, JG Webb - Catheterization and Cardiovascular Interventions, 2018

Transcatheter aortic valve implantation can be successful in selected patients with annuli beyond the current recommended limits for available transcatheter heart valves.… Hopefully in future we will have both a broader understanding and a broader range of options. Conflict of interest. Dr. Webb is a consultant to Edwards Lifesciences and ViVitro Labs. Publication cover image. Volume 91, Issue 6. May 1, 2018. Pages 1157-1158

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Marije E. Kamphuis; Gert Jan Pelgrim; Marcel J. W. Greuter; Riemer H. J. A. Slart; Cornelis H. Slump Proceedings Volume 10577, Medical Imaging 2018: Image Perception, Observer Performance, and Technology Assessment; 1057714 (2018); doi: 10.1117/12.2286337 Event: SPIE Medical Imaging, 2018, Houston, Texas, United States

...Myocardial perfusion imaging (MPI) is a commonly used diagnostic method in coronary artery disease (CAD)... ... In line with proper clinical decision-making, it is essential to assess institutional MPI test validity by confronting MBF assessment to a ground truth. Our research focuses on developing such validation instrument/method for MPI by means of simulating controlled myocardial perfusion in a phantom flow setup.... … All the data presented in this paper were obtained with the open circuit setup to prevent contrast recirculation. The used piston pump (Vivitro Superpump, Vivitro Labs, Victoria, Canada) generates programmable pulsatile flow

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H Saaid, P Segers, M Novara, T Claessens, P Verdonck - Experiments in Fluids, 2018

...The effects of the orientation of a prosthetic mitral valve in anatomical and anti-anatomical configurations have been investigated during the diastolic filling time... … A commercially available cardiovascular simulator (Vivitro Systems, Inc., Victoria, BC, Canada) that can impose and monitor different physiological pressure and flow conditions was adopted. The hydraulic piston pump was connected to the inner tank …

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S Houser, I Okafor, V Raghav, A Yoganathan - Journal of Visualization First Online: 16 February 2018

...The objective of this study was to characterize three distinct orientations (30°, 60° and 90°) of the non-parallel jet–vortex interaction in a simplified flow loop... … 1 Experimental setup of jet–vortex interaction flow loop. A programmable pulsatile pump (ViVitro SuperPump) allowed for controlled, isolated vortex rings to be ejected into the chamber, as shown in Fig. 2. The flow profile for vortex ring ejection is shown in Fig …

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Ram Ghosh, Gil Marom, Oren Rotman, Marvin J. Slepian, Saurabh Prabhakar, Marc Horner and Danny Bluestein -- Journal of Biomechanical Engineering doi:10.1115/1.4040600 History: Received November 06, 2017; Revised May 30, 2018

...All currently FDA-approved TAVR devices use tissue valves that were adapted to but not specifically designed for TAVR use. Emerging clinical evidence indicates that these valves may get damaged during crimping and deployment- leading to valvular calcification, thrombotic complications, and limited durability... ...Our research group has developed a novel polymeric prosthetic valve, which was optimized to reduce stresses on the leaflets, improve hemodynamics and has thrombogenic performance similar to that of a tissue valve... … The valves are then sutured to a nitinol stent for completion of the process. The valves' durability is now being assessed using a Vivitro Hi-Cycle System (Vivitro Labs, Inc … Hydrodynamic performance is being evaluated using the Vivitro left heart simulator (Vivitro Labs, Inc …

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M Jeyhani, S Shahriari, M Labrosse - Artificial Organs, 2017 First published: 23 November 2017

This in vitro study aims to evaluate the hemodynamic modifications following a simulated PEtER. A custom-made mitral valve was developed, and two configurations were tested: (i) a single-orifice valve with mitral regurgitation and (ii) a double-orifice mitral valve configuration following PEtER. … MATERIALS AND METHODS In vitro model For the purpose of this study, a ViVitro pulse duplicator (ViVitro Labs, Victoria, BC, Canada) was used (Fig. 1). This system is capable of reproducing physiological flow and pressure waveforms in left heart cavity models …

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Munirah Ismail, Foad Kabinejadian, Yen Ngoc Nguyen, Edgar Tay Lik Wui, Sangho Kim, Hwa Liang Leo - - Medical Engineering and Physics October 25, 2017

...The study utilises both 2-D and 3-D particle image velocimetry (PIV) to interrogate the flow patterns in the vicinity of the extra-cardiac tricuspid valves in an in vitro physiological flow loop, specifically at four measurement locations in the cavo-atrial anatomy. ... ... of the hepatic vein. In contrast, the SVC valve was fully implanted in the SVC. The mock circulatory system was driven by a pulse generator (SuperPump AR series, ViVitro Labs Inc., Victoria, BC, Canada). It comprised of an ultrasonic ...

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W Conlin, P Yu, V Durgesh - Bulletin of the American Physical Society, 2017

...The objective of this study is to identify the large-scale structures in the aneurysm, study temporal behavior, and quantify their interaction with the inflow condition. ... ... For this purpose, detailed Particle Image Velocimetry (PIV) measurements were performed at the center plane of an idealized aneurysm model for a range of inflow conditions. Inflow conditions were precisely controlled using a ViVitro SuperPump system. ...

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P Yu, V Durgesh, H Johari - Bulletin of the American Physical Society, 2017

...Studies have shown that hemodynamics is integral to developing an understanding of aneurysm formation, growth, and rupture. This investigation focuses on a comprehensive study of the impact of varying inflow conditions and aneurysm shapes on spatial and temporal behavior of flow parameters and structures in an aneurysm.... ... For this purpose, detailed Particle Image Velocimetry (PIV) measurements were performed at the center plane of an idealized aneurysm model for a range of inflow conditions. Inflow conditions were precisely controlled using a ViVitro SuperPump system. ...

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Chung-Dann Kan, MD, PhD, Jieh-Neng Wang, PhD, Wei-Ling Chen, PhD, Pong-Jeu Lu, PhD, Ming-Yao Chan, PhD, Chia-Hung Lin, PhD, Wan Chin Hsieh, MD The Journal of Thoracic and Cardiovascular Surgery, September 2017

...The current study investigated: (i) the function of the ePTFE trileaflet-valved conduits in an ex vivo experimental system and (ii) the short-term performance of the conduit in a porcine model to verify their clinical applicability.... ... valves. 168 Right ventricular function was simulated by using a digitally controlled hydraulic piston 169 SuperPump (ViViTro Labs, Victor, British Columbia, Canada), which generated a pulsating 170 flow to drive the chamber and send it into a compliant pulmonary artery. ...

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A. Desai, T. Vafaee, P. Rooney, J.N. Kearney, H.E. Berry, E. Ingham, J. Fisher, L.M. Jennings Journal of the Mechanical Behavior of Biomedical Materials 14 September 2017

The use of decellularised biological heart valves in the replacement of damaged heart valves ... ...The purpose of this study was to assess the effect of low concentration sodium dodecyl sulphate decellularisation on the in vitro biomechanical and hydrodynamic properties of cryopreserved human aortic and pulmonary roots.... ... performance of the valve roots. A viscoelastic impedance adapter (VIA; Vivitro System Inc., Victoria BC, Canada) was used to deliver a more physiological ventricle pressure and flow waveform in the simulator. This system allowed for ...

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Retta SM, Kepner J, Marquez S, Herman BA, S Shu MC, Grossman LW J Heart Valve Dis. 2017 Jan;26(1):72-80.

One of the first steps in qualifying a new prosthetic valve for eventual clinical use is preclinical flow performance testing in vitro... ...This collaborative effort between heart valve manufacturers and the Food and Drug Administration (FDA) was designed to evaluate the variability of the pulse duplicator test technology for pulsatile flow performance measurement in an interlaboratory round robin... ...A commercially available duplicator, the Vivitro system (Vivitro, Inc., Vancouver, Canada), was used at two centers. The design specifications are summarized in Table I....

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Yen Ngoc NguyenMunirah IsmailFoad KabinejadianChi Wei OngEdgar Lik Wui TayHwa Liang Leo - Cardiovascular Engineering and Technology 2017

The increased understanding of right heart diseases has led to more aggressive interventions to manage functional tricuspid regurgitation (FTR)... ...In this study, a novel in vitro mock circulatory system that incorporated a realistic tricuspid valve apparatus in a patient-specific silicon right ventricle (RV) was designed and fabricated... ... A closed ventricular chamber housing the silicon RV model was connected to a closed atrial chamber at one end, and was directly connected to the pulsatile wave-generating piston pump (SuperPump AR series, ViVitro Labs Inc., Victoria, BC, Canada) at the other end to simu ...

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