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Onur Dur, Keif Fitzgerald, Paul Muller, Chris Parker Thoratec Corporation, Sunnyvale, CA company slide
The HeartMate PHP is a 13F catheter-based trans-aortic heart pump with a collapsible distal portion that expands to 24F to provide minimally invasive acute hemodynamic stabilization and left ventricular unloading in both prophylactic and emergent clinical settings... Objective: To evaluate the interaction of the HeartMate PHP with native cardiovascular system via in vitro pulsatile mock flow loop testing. A custom-built pulsatile heart simulator adapted from Vivitro Pulse Duplicator (Vivitro Labs Inc., Canada) was tuned to generate physiological flow pressure waveforms while mimicking the preload sensitivity of the native heart.
Other Products Cited: Pulsatile Flow Simulation Pulse Duplicator
Visit SourceG. Tansley, S. Vidakovic, and J. Reizes; Artificial Organs: 24, Issue 6; 483 – 487.
The VentrAssist pump has no shaft or seal, and the device is unique in design because the rotor is suspended passively by hydrodynamic forces, and urging is accomplished by an integrated direct current motor rotor that also acts as the pump impeller. This device has led to many challenges in its fluidic design...
Other Products Cited: Heart Valve Testing SuperPump
Visit SourceYu, Yih-Choung; Boston, J. Robert; Simaan, Marwan A.; Miller, Phil J.; Antaki, James F.; ASAIO Journal: 47, Issue 3; 293-301; 2001.
A mathematical model describing the pressure-volume relationship of the Novacor left ventricular assist system (LVAS) was developed. The model consists of lumped resistance, capacitance, and inductance elements with one time varying capacitor to estimate the cyclic pressure generation of the pump using pump volume measurement.
Other Products Cited: SuperPump
Visit SourceMazur, Daniel E.; Osterholzer, Kathryn R.; Toomasian, John M.; Merz, Scott I.; ASAIO Journal: 54, Issue 5; 523-528; 2008.
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Visit SourceJ Cysyk, R Newswanger… - … in Medicine and …, 2011 - ieeexplore.ieee.org
Due to improved reliability and reduced risk of thromboembolic events, continuous flow left ventricular assist devices are being used more commonly as a long term treatment for end-stage heart failure. As more and more patients with these devices are leaving the hospital, a reliable control system is needed that can adjust pump support in response to changes in physiologic demand.
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Visit SourceChoon-Sik Jhun and Joshua P. Cysyk* – Artificial Organs Volume 38, Issue 4, pages 309–315, April 2014
End-systolic elastance and end-diastolic compliance have been used to quantify systolic and diastolic function of the left ventricle (LV). In this study, the effective end-systolic elastance, (EES)eff, end-systolic volume intercept, (V0)eff, and end-diastolic compliance of the LV were assessed at various levels of left ventricular assist device (LVAD) support.
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Visit SourceT Pirbodaghi, C Cotter, K Bourque – Artificial Organs, 2014
The magnetically levitated rotor makes it feasible to modulate the pump speed without concern for contact-bearing friction that can impede rotation. The pump was connected to a commercial LV simulator (ViVitro Systems, Victoria, BC, Canada), schematically illustrated in Fig. …
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