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Libby H. Welborn, Anna K. Himes, Ida E. Greenlee, Nyna J. DeWitt, Ava T. Burgess, Brandon K. Eberl, Olga Pierrakos, 2022 Systems and Information Engineering Design Symposium (SIEDS)
The aim of this paper is to: 1) showcase the design process of a quadleaflet ePTFE valved conduit with a diameter of 16mm or less and 2) offer a hemodynamic performance comparison. ...The proposed valve was tested using the ViVitro Pulse Duplicator under physiologic cardiac conditions... ...A comparison between the two ePTFE handmade valves (trileaflet and quadleaflet) demonstrated hemodynamic differences in regurgitation due to leaflet number. The handmade valves both showed increased regurgitation compared to a Carbomedics valve (commercially available design). Regurgitation had varying effects on pressure gradients and cardiac output...
Other Products Cited: Heart Valve Testing Pulse Duplicator
Visit SourceK.Yu. Klyshnikov, P.S. Onischenko, Е.А. Ovcharenko, СТМ, 2022, vol. 14, No.2
The aim of the study was to study the complex biomechanics of the aortic valve prosthesis and to analyze the effect of frame mobility on the stress-strain state and geometry of the valve leaflet apparatus using a numerical simulation method, which reproduces the qualitative and quantitative results of its bench tests. ...The simulation was validated by comparing the results of numerical and bench simulation on the ViVitro Labs hydrodynamic system (ViVitro Labs Inc., Canada)... ...The results of the UniLine prosthesis biomechanics modeling have demonstrated that mobility of the frame struts of the heart valve prosthesis is a crucial aspect in assessing the effectiveness of the leaflet apparatus geometry and may be a negative factor in case of a highly elastic leaflet material...
Other Products Cited: Analysis and Computational Modeling Pulse Duplicator
Visit SourcePaulo Yu, Vibhav Durgesh, Fluids, 2022, 7, 165.
Aneurysms are localized expansions of blood vessels which can be fatal upon rupture. Studies have shown that aneurysm flows exhibit complex flow phenomena which consist of single or multiple vortical structures that move within the flow cycle. ...Rep and α were the inflow parameters used to match and simulate the conditions in the human circulatory system. These inflow parameters were precisely controlled with a ViVitro Labs Inc. SuperPump system... ...Both POD and DMD are capable analysis tools to investigate the spatial and temporal behavior of large-scale structures of a given flow field. POD and DMD can be used to create mathematical models to look into the flow evolution in sufficiently high detail and at any time step...
Other Products Cited: Flow Visualization SuperPump
Visit SourceSalwa B. Anam, Brandon J. Kovarovic, Ram P. Ghosh, Matteo Bianchi, Ashraf Hamdan, Rami Haj-Ali & Danny Bluestein - Cardiovascular Engineering and Technology (2022)
Bicuspid aortic valve (BAV) is the most common congenital cardiac malformation, which had been treated off-label by transcatheter aortic valve replacement (TAVR) procedure for several years, until its recent approval by the Food and Drug Administration (FDA) and Conformité Européenne (CE) to treat BAVs. ...Materials and Methods Patient-specific in silico models and 3D printed replicas of 3 BAV patients with different degrees of post-TAVR paravalvular leakage (PVL) were created. Patient-specific TAVR device deployment was modeled in silico and in vitro—following … ...PVL degree and locations were consistent with the clinical data. Cross-validation comparing the stent deformation and the flow parameters between the in silico and the in vitro models demonstrated good agreement....
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Visit SourceL. van de Velde, E. Groot Jebbink, B. A. Zambrano, M. Versluis, J. Tessarek & M. M. P. J. Reijnen: CardioVascular and Interventional Radiology (2022)
...To assess this flow diverting strategy for popliteal aneurysms, flow profiles and thrombus formation likelihood were investigated in popliteal aneurysm models... ...The model was placed in a circulating flow set-up with a blood-mimicking fluid (Fig. 3). At the inlet, a hydraulic piston pump (SuperPump, ViVitro labs, Victoria, Canada) was used to enforce time-varying forward flow...
Other Products Cited: Pulsatile Flow Simulation Stent Testing SuperPump
Visit SourcePaulo Yu, Vibhav Durgesh, Fluids, 2022
...Rep and α were two inflow parameters used in this study, and these were controlled using a ViVitro Labs Inc. (Victoria, BC, Canada) SuperPump system...POD provides a method for analyzing complex flow phenomena in great detail. It can be used to study a variety of unsteady, physiological flows to understand the behavior of energetic flow structures..
Other Products Cited: Flow Visualization SuperPump
Visit SourceH. Appa, K. Park, D. Bezuidenhout, B. van Breda, B. de Jongh, J. de Villiers, R. Chacko, J. Scherman, C. Ofoegbu, J. Swanevelder, M. Cousins, P. Human, R. Smith, F. Vogt, B, K. Podesser, C. Schmitz, L. Conradi, H. Treede, H. Schröfel, T. Fischlein, M. Grabenwöger, X. Luo, H. Coombes, S. Matskeplishvili, D. F. Williams, P. Zilla, Front. Cardiovasc. Med., 03 March 2022
...Hydrodynamic testing to determine gradients (ΔP), effective orifice areas (EOA) and regurgitant fractions was performed in a pulse duplicator (Cardiac Output: 5 L/min; 37°C; 70 bpm; Stroke Volume: 32 ± 5 ml; Systolic Phase Duration of 35 ± 5%) (ViVitro Labs Inc; Victoria, BC, Canada)...The BE TAVR system met all requirements for which it was developed...
Other Products Cited: Heart Valve Testing Pulse Duplicator
Visit SourceY. Zhu, A. M. Imbrie-Moore, R. J. Wilkerson, M. J. Paulsen, M. H. Park & Y. Joseph Woo, BMC Cardiovascular Disorders volume 22, Article number: 73 (2022)
...The left heart simulator, which has been previously described, features a pulsatile linear piston pump (ViVitro Superpump, ViVitro Labs, Victoria, British Columbia, Canada) to generate physiologic parameters using the pump controller and software (ViVitest Software, ViVitro Labs) programmed in accordance with ISO 5840 standards for in vitro valve testing...The mitral annular dilation system successfully generated an ex vivo mitral annular dilation model with MR...
Other Products Cited: Ex ViVo Simulation Heart Valve Repair Pulse Duplicator
Visit SourceN Norris, K Lewis, C Settanni, T Becker, A Ducruet, Journal of NeuroInterventional Surgery 2021, 13 (Suppl 1)
...Physiologically-relevant patient flow parameters were tuned within the system using a Super Pump AR (ViVitro Labs)...This in-vitro aneurysm flow model utilized the latest in UV-cured 3D-printing techniques to provide a realistic simulation of neurovascular tortuosity and aneurysm device delivery...
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Visit SourceM. Alizadeh, M. Cote, A. Branzan Albu, Proceedings of the IEEE/CVF Winter Conference on Applications of Computer Vision 2022
...Our experimental setup to collect high-quality videos and pressure and velocity data involves tricupsid BHVs mounted in the Pulse Duplicator device from ViVitro Labs...Experiments on four cases that include three different tricuspid BHVs yielded promising results, with the DTW scores showing a good coherence with respect to the simulations...
Other Products Cited: Heart Valve Testing Pulse Duplicator
Visit SourceM. Marin-Cuartas, Y. Zhu, A. M. Imbrie-Moore, M. H. Park, R. J. Wilkerson, M. Leipzig, P. K. Pandya, M. J. Paulsen, M. A. Borger, Y. J. Woo, Interactive CardioVascular and Thoracic Surgery (2021) 1–9
...The severity of acute papillary muscle (PM) rupture varies according to the extent and site of the rupture. However, the haemodynamic effects of different rupture variations are still poorly understood...A 3D printer (Carbon 3D, Redwood City, CA, USA) was used to prototype a modular left heart (left atrium and ventricle) and was mounted to a pulsatile linear piston pump (ViVitro Superpump; ViVitro Labs, Victoria, BC, Canada)...
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Visit SourceA. Imbrie-Moore, Y. Zhu, T. Bandy-Vizcaino, M. Park, R. Wilkerson, Y. Woo, Annals of Biomedical Engineering, 49
Driven by a pulsatile linear piston pump (ViVitro Superpump, ViVitro Labs, Victoria, BC, Canada) which generates physiologic hemodynamics in accordance with ISO 5840 in vitro cardiac valve testing standards.
Other Products Cited: Heart Valve Repair SuperPump
Visit SourceB. Ncho, A. Siefert, V. Sadri, J. Ortner, A. Yoganathan. Journal or Med. Devices
The physiologic pressures and flows were achieved by adjustment of systemic resistance and compliance elements, and flow driven from a piston pump (Vivitro Labs Inc. Victoria, Canada).
Other Products Cited: Flow Visualization Heart Valve Testing SuperPump
Visit SourceP. Yu, V. Durgesh, Journal of Biomechanical Engineering, 5
The inflow conditions are precisely controlled using a ViVitro SuperPump system where nondimensional fluid parameters such as peak Reynolds number (Rep) and Womersely number (α) are varied from 50–270 and 2–5, respectively.
Other Products Cited: Flow Visualization SuperPump
Visit SourceJ. Westenberg, H. van Assen, P. van den Boogaard, J. Goeman, H. Saaid, J. Voorneveld, J. Bosch, S. Kenjeres, T. Claessens, P. Garg, M. Kouwenhoven, H. Lamb, Magnetic Resonance in Medicine
A pulsatile hydraulic piston pump (Vivitro Labs, Victoria, Canada) was connected to the tank with semirigid tubing. This pump, positioned outside the scanner room, generated a sinusoidal-like pulsatile waveform with 70-bpm frequency without net flow, resulting in a pressure waveform inside the tank that created contraction of the filled LV phantom with a 300-ms systolic period and 50-mL stroke volume.
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Visit SourceR. Whiting, E. Sander, C. Conway, T. J. Vaughan. 2021.
...To evaluate the hydrodynamic performance of each valve, in vitro bench testing was performed using a Vivitro Pulse Duplicator (Figure 2a) (Vivitro Labs, Inc. Victoria, B.C.) according to ISO 5840...
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Visit SourceS. Zhan-Moodie, D. Xu, K. S. Suresh, Q. He, D. Onohara, K. Kalra, R. A. Guyton, E. L. Sarin, M. Padala. JTCVS Open.
...actuating pump with a viscoelastic impedance (Superpump, Vivitro Labs, London, ON) was connected to the LV, and programmed to generate physiological left ventricular pressures. 0.9% saline was used as the working medium in this flow loop...
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Visit SourceC. D. Hsu, A. Mirza, R. Matheny, S. Ramaswamy. Structural Heart. Vol. 5.
...hydrodynamic testing of the valves mounted in mitral and tricuspid positions were performed using a pulse duplicator system (ViVitro Labs) using 0.9% saline solution...
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Visit SourceF. Stieglmeier, M. Grab, F. König, J. Büch, C. Hagl, N. Thierfelder. Journal of the Mechanical Behavior of Biomedical Materials. Vol. 118.
… was applied, was documented. 2.9. Durability testing. To investigate the long-term durability, patches were tested in a modified high-cycle (HC) system (HiCycle Durability Tester; ViVitro Labs Inc., Victoria, CAN). A 3D printed …
Other Products Cited: HiCycle Durability Tester Tissue Engineering
Visit SourceP. Yu, V. Durgesh, T. Xing, R. Budwig. Journal of Biomedical Engineering. Vol. 143.
… vectors in the sac region. 3.3 Pump System. To generate controlled inflow conditions for this study, a piston pump (ViVitro Labs Inc. SuperPump Sys- tem AR Series, Victoria, BC, Canada) was used. The piston pump system …
Other Products Cited: Flow Visualization SuperPump
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