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Michael A. Bielecki, Julianne H. Spencer, Paul A. Iaizzo
Pumping New Life into Heart Research: How ViVitro's Superpump is Changing TAVR Studies In this study, researchers took a unique approach by reanimating swine and human hearts with a ViVitro Superpump to investigate how TAVR implantation affects coronary pressure. Using the Superpump and detailed CT scans, they measured what they call the Estimated Leaflet to Ostium Distance, or ELOD, and found a clear correlation: the shorter that distance, the more coronary pressure could drop. In other words, by getting these hearts beating again in a lab setting, they demonstrated that ELOD might be a better predictor of coronary obstruction risk than some traditional measurements. It’s a solid example of how ViVitro’s technology is helping refine our understanding of heart valve procedures, all without the need for animal or patient trials.
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Visit SourceMerhi Y, Montero KL, Johansen P, Mäntysalo M, Agarwala S, ChemRxiv, 2025
We assessed the piezoelectric performance of poly-L-lactic acid (PLLA) films, fabricated using solvent casting and processed using uniaxial stretching and thermal annealing, through tapping, straining, and force- and vibration-sweep tests. The ventricular chamber was connected to a digitally controlled piston pump (Super Pump, ViVitro, Victoria, BC, Canada), which provided pulsatile flow to simulate left ventricular ejection into the aortic root. These results establish the feasibility of PLLA-based sensors for real-time biomechanical feedback during and after cardiovascular surgeries, paving the way for next-generation monitoring technologies that enhance patient outcomes.
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Visit SourceJohn Davidson, Sangjin Ryu Journal of Visualization pp 1-9 First online: 30 May 2016
Soap bubble blowing has long been an amusement for humans, and the process involves pinch-off similarly to liquid drops and gas bubbles. ... 2.4.2 Measurement using a Pitot tube. To validate the image-based speed measurement, we measured the airflow speed at the center of the nozzle outlet (U e ) using a Pitot static tube (PAA-8-KL, United Sensor Corp.) with pressure transducers (Pulse Duplicator, ViVitro Labs). ...
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Visit SourceNg, Kim-Gau; Ting, Choon-Meng; Yeo, Joon-Hock; Sim, Kwang-Wei; Peh, Wee-Leng; Chua, Ngak-Hwee; Chua, Ngak-Kwong; Kwong, Frank; Blood Pressure Monitoring: 9, Issue 3; 149-165.
The MediWatch is a wrist-mounted noninvasive blood pressure monitor designed to capture the radial pulse waveform using arterial tonometry and yield blood pressure measurements when the waveform is calibrated. An early prototype of this monitor uses a pulse-sensing system with a cylindrical plunger to applanate the radial artery. This prototype was evaluated against simulated blood pressure generated by a pneumatic pressure-pulse generator.
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Visit SourceAcute and Chronic Swine Rete Arteriovenous Malformation Models: Hemodynamics and Vascular Remodeling
A. K. Wakhlooa, B. B. Liebera, R. Siekmannc, D. J. Ebera and M. J. Gounisa; American Journal of Neuroradiology: 26; 1702-1706.
Liquid embolic agents are increasingly gaining importance in the embolization of cerebral arteriovenous malformations (AVMs). Currently, the most commonly used agent is N-butyl 2-cyanoacrylate (NBCA). Various NBCA mixtures, arterial hypotension, and Valsalva maneuver (increased positive end-expiratory pressure) during the injection of the acrylate have been used to address hemodynamic and architectural variations of an AVM; however, the precise in vivo polymerization, distribution, and kinetics of NBCA mixtures are unknown. We investigated the effect of different acrylate/Lipiodol mixtures and the addition of glacial acetic acid (GAA) on the penetration, dispersion, and injection force of NBCA.
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Visit SourceMorteza Gharib and Masoud Beizaie; Annals of Biomedical Engineering: 31, Issue 6; 678-685; 2003.
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Visit SourceZhang, Pei; Yeo, Joon Hock; Hwang, N H. C.; ASAIO Journal: 52, Issue 4; 391-397; 2006.
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Visit SourceZhang, Pei; Yeo, Joon Hock; Qian, Ping; Hwang, Ned H. C.; ASAIO Journal: 53, Issue 5; 530-536; 2007.
The particle image velocimetry technique was used to study the shear field across a transparent mechanical heart valve model in one cardiac cycle. Shear stress was continuously increased until peak systole and high turbulent stress was observed at the orifice of the central channel and also around the occluder trailing tips.
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