Articles Related to SuperPump

Paulo Yu, Vibhav Durgesh, Tao Xing, Ralph Budwig -J Biomech Eng. Published Online: February 4, 2021

Aneurysms are localized expansions of weakened blood vessels that can be debilitating or fatal upon rupture... ...the objective of this study was to demonstrate the application of Proper Orthogonal Decomposition (POD) to study the impact of different inflow conditions on energetic flow structures and their temporal behavior in an aneurysm. To achieve this objective, experiments were performed on an idealized rigid sidewall aneurysm model. A piston pump system was used for precise inflow control, i.e., peak Reynolds number ($Re_p$) and Womersley number ($\alpha$) were varied from 50-270 and 2-5, respectively.... … These settings provided approximately 9000 vectors in the pipe region, 6000 vectors in the neck region, and 6800 vectors in the sac region. 3.3 Pump system To generate controlled inflow conditions for this study, a piston pump (ViVitro Labs Inc …

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Daniele Dipresa, Panagiotis Kalozoumis, Michael Pflaum, Ariana Peredo, Bettina Wiegmann, Axel Haverich, Sotirios Korossis - J Biomech Eng. Paper No: BIO-20-1042 Published Online: January 19, 2021

Extracorporeal membrane oxygenation (ECMO) has been used clinically for more than 40 years as a bridge to transplantation, with hollow-fiber membrane (HFM) oxygenators gaining in popularity due to their high gas transfer and low flow resistance.... ...In this study, the blood flow through two HFM oxygenators, including the commercially-available iLA® MiniLung Petite Novalung (Xenios AG, Germany) and an experimental one for the rat animal model, was modelled using computational fluid dynamics (CFD), with a view to assessing the magnitude and distribution of the shear stress on the wall of the hollow fibers and flow fields in the oxygenators... … developed, which comprised a flow meter (Model 501, Carolina Medical Electronics, NC, US), heat exchanger and temperature controller (HE9991, Vivitro Labs, Victoria, CA), centrifugal pump (Medtronic Bio-Medicus 520C Bio …

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Annabel M. Imbrie-Moore, Matthew H. Park, Michael J. Paulsen, Mark Sellke, Rohun Kulkami, Hanjay Wang, Yuanjia Zhu, Justin M. Farry, Alexandra T. Bourdillon, Christine Callinan, Haley J. Lucian, Camille E. Hironaka, Daniela Deschamps and Y. Joseph Woo - Journal of the Royal Society Interface, December 2020

Papillary muscles serve as attachment points for chordae tendineae which anchor and position mitral valve leaflets for proper coaptation. As the ventricle contracts, the papillary muscles translate and rotate, impacting chordae and leaflet kinematics; this motion can be significantly affected in a diseased heart... ...We developed and implemented image-guided papillary muscle (IPM) robots to mimic the precise motion of papillary muscles. The IPM robotic system was designed with six degrees of freedom to fully capture the native motion... … The simulator features a pulsatile linear piston pump (ViVitro Superpump, ViVitro Labs, Victoria, BC, Canada) programmed to produce a physiologic waveform in compliance with ISO 5840 standards for in vitro valve testing …

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Sanjiv Gunasekera, Olivia Ng, Shannon Thomas, Ramon Varcoe, Charitha de Silva & Tracie Barber - Experiments in Fluids, 2020

The arteriovenous fistula (AVF), which is a vasculature created for end-stage renal disease patients who require haemodialysis, is susceptible to many vascular diseases. ...The current study is an investigation of the complex three-dimensional flow within a physiological AVF geometry, using tomographic particle image velocimetry... … The ViVitro Superpump (ViVitro Labs Inc., BC, Canada) was used as the flow source and a network of rigid Tygon tubing inclusive of valves, to simulate vascular resistance, and air-filled syringes, to simulate vascular compliance, connected the model to the pump …

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Michael J. Paulsen, Annabel M. Imbrie-Moore, Michael Baiocchi, Hanjay Wang, Camille E. Hironaka, Haley J. Lucian, Justin M. Farry, Akshara D. Thakore, Yuanjia Zhu, Michael Ma, John W. MacArthur Jr, Y. Joseph Woo - Circulation, 2020

...The specific impact of such neosinuses on valvular and root biomechanics and the potential influence on long-term durability are unknown... ...Using a custom 3-dimenstional–printed heart simulator with porcine aortic roots (n=5), the anticommissural plication, Stanford modification, straight graft (SG), Uni-Graft, and Valsalva graft configurations were tested in series using an incomplete counterbalanced measures design, with the native root as a control, to mitigate ordering effects... ... the system is comprised of a modular 3-dimensional–printed (Carbon M2, Carbon 3D Inc., Redwood City, CA) and machined enclosure mounted to a pulsatile linear actuator (Superpump, Vivitro Labs, Vancouver, Canada).

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Jana Fuchsberger Philipp Aigner Gundolf Haase Steven Niederer Heinrich Schima Gernot Plank Elias Karabela - September 2020 preprint rxiv.org

Simulating the interaction of fluids with immersed moving solids is playing an important role for gaining a better quantitative understanding of how fluid dynamics is altered by the presence of obstacles and, vice versa, which forces are exerted on the solids by the moving fluid... ...application problems with focus on understanding the effect of solids on altering fluid dynamics. In this study we report on the development of a novel method for such applications. In our method rigid moving obstacles are incorporated in a fluid dynamics context using concepts from porous media theory. Based on the Navier-Stokes-Brinkman equations... ...and a piston pump (SuperPump, ViVitro Labs Inc., Victoria, BC, Canada) were used to generate stationary and pulsating inflows....

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Yuanjia Zhu, Annabel M. Imbrie-Moore, Michael J. Paulsen, Bryant Priromprintr, Matthew H. Park, Hanjay Wang, Haley J. Lucian, Justin M. Farry & Y. Joseph Woo - Journal of Cardiovascular Translational Research (2020)

To simulate Aortic Regurgitation (AR), four porcine aortic valves were explanted, and the commissure between the two largest leaflets was detached and re-implanted 5 mm lower to induce cusp prolapse. … 1c), which has been previously described in detail [17, 18]. In brief, the simulator encompasses a programmable pulsatile linear piston pump (ViVitro Superpump, ViVitro Labs, Victoria, BC, Canada) that is attached to a custom left ventricular chamber …

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Sean Guo‐Dong Tan, Jimmy Kim Fatt Hon, Yen Ngoc Nguyen, Sangho Kim, Hwa Liang Leo - Artificial Organs 22 July 2020

This study aims to investigate the effect of orifice shape and its position with respect to the posterior wall of the ventricle on vortical formation and turbulence intensity in the LV, by utilizing four separate orifice configurations within an in vitro left heart simulator. … in a native healthy heart as described in a prior study by GDS Tan et al.[25] was utilized in this study. A pulsatile pump (ViVitro Labs Inc., Victoria, BC, Canada) was employed to propel the blood analog with properties that are described in table 2 through the loop …

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Bhullar, Arpin Singh - UBC Theses and Dissertations 2020

...research topic of designing a radical mechanical heart valve prosthesis that leveraged novel design elements to mitigate anticoagulant therapy and improve patient quality of life... ....problems have plagued the most common form of MHVs, bileaflet mechanical heart valves (BMHVs), for decades as their designs have stagnated.... ... This research was conducted to design and validate a BMHV that would have similar hemodynamic properties to native heart valves, enabling implantation without reliance on post-operative anti-coagulants.... ... modern, digital ViVitro SuperPump and its power and control system which combined, produce the user-selected waveform for testing...

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Annabel M. Imbrie-Moore, Cole C. Paullin, Michael J. Paulsen, Frederick Grady, Hanjay Wang, Camille E. Hironaka, Justin M. Farry, Haley J. Lucian. Y. Joseph Woo - Medical Engineering & Physics Available online 31 January 2020

...This work shows the design and implementation of a 3D-printed valve dilation device to preferentially dilate the posterior mitral valve annulus... ...In brief, a custom 3D-printed left heart chamber (Fig. 2A) was mounted to a pulsatile linear piston pump (ViVitro Superpump, ViVitro Labs, Victoria, BC, Canada) with the ability to generate physiologic conditions … ...this annular dilation device provides the means to investigate the design and optimization of novel annuloplasty rings....

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Michael J Paulsen, Annabel M Imbrie-Moore, Hanjay Wang, Jung Hwa Bae, Camille E Hironaka, Justin M Farry, Haley J Lucian, Akshara D Thakore, John W MacArthur, Jr, Mark R Cutkosky, Y Joseph Woo - European Journal of Cardio-Thoracic Surgery, ezz258

Posterior ventricular anchoring neochordal (PVAN) repair is a non-resectional technique for correcting mitral regurgitation (MR) due to posterior leaflet prolapse, utilizing a single suture anchored in the myocardium behind the leaflet... ...Porcine mitral valves were mounted in a 3-dimensional-printed heart simulator and chordal forces, haemodynamics and echocardiography were collected at baseline, after inducing MR by severing chordae, and after PVAN repair.... ...PVAN repair eliminates MR by positioning the posterior leaflet for coaptation, distributing forces throughout the valve....

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Yen Ngoc Nguyen, Edgar Lik Wui Tay, Foad Kabinejadian, Chi Wei Ong, Munirah Ismail, and Hwa Liang Leo -American Journal of Physiology-Heart and Circulatory Physiology 11 OCT 2019

The deteriorating nature of severe functional tricuspid regurgitation (FTR) has led to the heightened interest in this pathology... ...In this study, the hemodynamics of the right ventricle (RV) after (i) clover edge-to-edge tricuspid repair and (ii) double orifice tricuspid repair was evaluated in three right heart models using an ex vivo pulsatile platform emulating severe FTR with the aid of stereoscopic particle image velocimetry... … circulation (35). A closed ventricular chamber housing the silicon RV model was directly 184 connected to the pulsatile wave-generating piston pump (SuperPump AR series, ViVitro Labs 185 Inc., Victoria, BC, Canada) to …

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Ong, C. W.; Kabinejadian, F.; Xiong, F.; Wong, Y. R.; Toma, M.; Nguyen, Y. N.; Chua, K. J.; Cui, F. S.; Ho, P.; Leo, H. - Journal of Applied Fluid Mechanics . Nov2019, Vol. 12 Issue 6, p1855-1872. 18p.

Thoracic aortic aneurysm (TAA) is a severe cardiovascular disease with a high mortality rate, if left untreated... ...In order to gain more insight on TAA formation, we developed a computational framework in vitro to investigate and compare the flow patterns between pre-aneurismal and post-aneurismal aorta using a deformable wall model... ...The pulsatile flow was created using a piston pump (SuperPump AR series, ViVitro Labs Inc., Victoria, BC, Canada) generating the inlet velocity profile with the How rate of 4 L/min at the frequency of 1 Hz, extracted from the literature …

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C Settanni, T Becker, A Ducruet, W Merritt, A Huckleberry - Journal of NeuroInterventional Surgery (JNIS) Volume 11, Issue Suppl 1

Although current microcatheter technologies have advanced in recent years, corresponding endovascular devices still lag behind... ...This research project includes development of innovative in vitro aneurysm vessel model with complex side branching.... … communicating (ACA) bifurcation. Flow is regulated through the use of a Super Pump AR (ViVitro Labs). This 3D printed model will be implemented in an in vitro flow model that enables systemic data collection. A data acquisition … ...The in vitro model is used to simulate and quantify short-and long-term viability of new biomaterials for brain aneurysm embolization...

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Immanuel David Madukauwa-DavidVahid SadriPrem A MidhaVasilis BabaliarosCyrus AidunAjit P. Yoganathan - Annals of Biomedical Engineering First Online: 16 July 2019

Transcatheter heart valve (THV) leaflet thrombosis in the neo-sinus and associated reduced leaflet motion is of clinical concern due to risks of embolism and worsened valve hemodynamics... ...We tested two replicas of FDA approved commercial THVs—intra-annular and supra-annular (similar to the SAPIEN 3 and CoreValve families)—in a left heart simulator with coronary flow... … The Georgia Tech left heart simulator is shown in Fig. 2a. The main flow rate was driven by the primary piston pump (Vivitro Labs Inc. Victoria, Canada); wall-tapped pressure transducers (Deltran DPT-200, Utah Medical Products Inc

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MJ Paulsen, JH Bae, A Imbrie-Moore, H Wang, CE Hironaka, JM. Farry, H Lucian, AD Thakore, MR Cutkosky, WJ Woo … - Journal of Biomechanical Engineering Accepted manuscript posted July 1, 2019 2019

Few technologies exist that can provide quantitative data on forces within the mitral valve apparatus... Using FBG sensors, we created a force-sensing neochord that mimics the natural shape and movement of native chordae.... … Redwood City, CA, USA) was mounted to a programmable pulsatile linear piston pump (ViVitro Superpump, ViVitro Labs, Victoria, BC, Canada) with the ability to generate physiologic conditions using the pump controller and …

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Chi Wei Ong, Fei Xiong, Foad Kabinejadian, Gideon Praveen Kumar, Fang Sen Cui. Gongfa Chen, Pei Hoe, HwaLiang Leo - Journal of Biomechanics Available online 19 January 2019

Thoracic endovascular aortic repair (TEVAR) has been introduced as a less invasive approach to the treatment of thoracic aortic aneurysm (TAA). However, the effectiveness of TEVAR in the treatment of TAA is often limited due to the complex anatomy of aortic arch... ...This study proposes a novel stent graft design with slit perforations that can positively alter the hemodynamics at the aortic arch while maintaining blood flow to supra-aortic branches... … flow preservation at side branches. The system was driven by a pulse generator (SuperPump AR series, ViVitro Labs Inc., Victoria, BC, Canada) at a flow rate of 5 L/min and a pulse rate of 1 Hz. The reservoir level and mechanical …

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Jonas Rasmussen, Søren Nielsen Skov, Ditte Bruus Nielsen, Ida Lindhardt Jensen, Marcell Juan Tjørnild, Peter Johansen, Vibeke E. Hjortdal - Journal of Cardiothoracic Surgery December 2019, 14:6

Management of congenital malformations of the pulmonary artery and valve can be challenging. The severity often demands early intervention, which is rarely definitive due to the natural growth and multiple surgeries may be required... ...In this study, a simple valve design supported by an absorbable proximal stabilization ring is evaluated both in-vitro and in-vivo... … In-vitro model and testing. All in-vitro testing was carried out in a pulsatile flow model using water as the test fluid (Fig. 2). Pulsatile flow and pressure were generated with an electromechanical piston pump (VSI Superpump, Vivitro Labs, Victoria, Canada) …

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Diya Wang; Boris Chayer ; François Destrempes ; François Toumoux ; Guy Cloutier - 2018 IEEE International Ultrasonics Symposium (IUS) 20 December 2018

Aortic stiffness is altered by cardiovascular diseases and exacerbated in innate or pathological conditions, which might be detected by noninvasive vascular elastography.... ...results suggest that the proposed model could detect and evaluate aortic aneurysm stiffness and may be useful clinically for the early and timely detection of degraded mechanical properties to impact patient outcomes.... … Hz. Normal and aneurysm aortic deformations were compared by pulsing mimicing vessels at 60 bpm, using a hydraulic pulse duplicator within a left ventricular model (Superpump system, Vivitro Inc., Victoria, BC, Canada) …

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Keyvan Amini Khoiy, Kourosh T. Asgarian, Francis Loth, Rouzbeh Amini - PLOS ONE Published: November 8, 2018

Chordae rupture is one of the main lesions observed in traumatic heart events that might lead to severe tricuspid valve (TV) regurgitation... ...we investigated the changes on TV geometry, mechanics, and function of ex-vivo porcine hearts following chordae rupture... … The schematic of this apparatus is shown in Fig 1. In short, a positive displacement pump (SuperPump AR Series, Vivitro Labs, Inc., Victoria, BC, Canada) was utilized to induce passive beating in porcine hearts …

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