Articles Related to Tissue Engineering
- Endovascular Simulator
- Ex ViVo Simulation
- Flow Visualization
- Heart Valve Repair
- Heart Valve Testing
- HiCycle Durability Tester
- MRI compatibility
- Pressure Measurement System
- Pulsatile Flow Simulation
- Pulse Duplicator
- Stent Testing
- Ultrasound Measurements
- VAD Testing
Miss Brittany A. Gonzalez, Miss Elnaz Pour Issa, Mr. Omkar V. Mankame, Miss Jenniffer Bustillos, Mr. Antonio Cuellar, Mr. Andres J. Rodriguez, Dr. Frank Scholl, Dr. Steven Bibevski, Dr. Lazaro Hernandez, Mr. Vincent Brehier, Mr. Mike Casares, Dr. Krishna Rivas, Dr. Pablo Morales, Mr. Jesus Lopez, Dr. Joseph Wagner, Dr. Jennifer Bibevski, Dr. Arvind Agarwal, Dr. Florence George, and Dr. Sharan Ramaswamy - Tissue Engineering Part A. December 5, 2019
Conceptually, a tissue engineered heart valve (TEHV) would be especially appealing in the pediatric setting since small size and somatic growth constraints would be alleviated. Here, we utilized porcine small intestinal submucosa (PSIS) for valve replacement... … the Dacron tubes housing the PSIS valves were measured in order to secure the valve‐in‐ conduit (Figure 1) in the mitral position within a pulse duplicator system (ViVitro Labs, Victoria, BC) … A pulse duplicator system… ... Our findings suggest that the altered structural responses of PSIS, post-fatigue, rather than de novo tissue formation, are primarily responsible for the valve’s ability to accommodate somatic growth during the acute phase (90 days) following mitral valve replacement...Visit Source
Andrew K. Capullia, Maximillian Y. Emmerta, b, c, Francesco S. Pasqualinia, b, Debora Kehlb, Etem Caliskanb, c, Johan U. Linda, Sean P. Sheehya, Sung Jin Parka, Seungkuk Ahna, Benedikt Webera, b, Josue A. Gossa, Simon P. Hoerstrupa, b, Kevin Kit Parkera; Biomaterials Volume 133, July 2017, Pages 229–241
Tissue engineered scaffolds have emerged as a promising solution for heart valve replacement because of their potential for regeneration. However, traditional heart valve tissue engineering has relied on resource-intensive, cell-based manufacturing, which increases cost and hinders clinical translation. ...We demonstrated controlled modulation of these scaffold parameters and show initial biocompatibility and functionality in vitro...
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Cole Feagler, Zeeshan Syedain and Robert Tranquillo University of Minnesota College of Science and Engineering Poster Report
While most commercial valves today use chemically-fixed porcine tissue in the construction of the replacement valves, the Tranquillo group has been exploring the use of decellularized, engineered tissue as leaflet material... ...The goal of this project was to engineer a commissure design to mitigate valve failure through tissue tearing, and to improve overall valve hemodynamics. (I.e. reduction of PVL)... ...Prototype TEHVs were tested to failure using a ViVitro Labs pulse duplicator, running custom LabView data acquisition software...Visit Source
Clara Seaman, Andrew McNally, Stephen Biddle, Lauren Jankowski, Philippe Sucosky Presented in part at the 2013 Biomedical Engineering Society Conference, September 2013, Seattle, WA, and at the 2013 ASME Summer Bioengineering Conference, June 2013, Sunriver, OR, USA
The study aim was to develop a laboratory protocol for the fabrication of tissue valve models mimicking mild and moderate calcific stenosis, for future use in flow studies. ... near-physiologic hemodynamics. The flow loop was driven by a programmable piston pump (Vivitro), and included resistance and compliance units to mimic the characteristics of the systemic vascular tree (Fig. 3A). The system ...Visit Source
Steven Goldstein, PhDa, David R. Clarke, MDb, Steven P. Walsh, PhDa, Kirby S. Black, PhDa, Mark F. O’Brien, MDc; The Annals of Thoracic Surgery: 70; 1962-1969; 2000.
Tissue engineering approaches utilizing biomechanically suitable cell-conductive matrixes should extend xenograft heart valve performance, durability, and growth potential to an extent presently attained only by the pulmonary autograft. To test this hypothesis, we developed an acellular, unfixed porcine aortic valve-based construct. The performance of this valve has been evaluated in vitro under simulated aortic conditions, as a pulmonary valve replacement in sheep, and in aortic and pulmonary valve replacement in humans.
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ZH Syedain, LA Meier, JM Reimer… – Annals of biomedical …, 2013 – Springer
A novel tissue-engineered heart valve (TEHV) was fabricated from a decellularized tissue tube mounted on a frame with three struts, which upon back-pressure cause the tube to collapse into three coapting "leaflets." The tissue was completely biological, fabricated from ovine fibroblasts dispersed within a fibrin gel,...
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Development and characterization of acellular porcine pulmonary valve scaffolds for tissue engineering
J Luo, SA Korossis, SPP Wilshaw, LM Jennings… – Tissue Engineering, 2014
… testing. The flow simulator has been described previously. 27 It mimicked the right heart and was controlled and monitored by the ViviTest software (Vivitro Systems Inc). The simulator was set up as described by Korossis et al. …Visit Source