中国地区询价 
1 (250) 388-3531 
+33 4 86 68 68 10 
Articles Related to Heart Valve Testing
Other Products
- Accessories
- Analysis and Computational Modeling
- Applications
- Endovascular Simulator
- Ex ViVo Simulation
- Flow Visualization
- Heart Valve Repair
- HiCycle Durability Tester
- MRI compatibility
- Pressure Measurement System
- Products
- Pulsatile Flow Simulation
- Pulse Duplicator
- Software
- Stent and Stent/Graft
- SuperPump
- TAVI
- Tissue Engineering
- Ultrasound Measurements
- VAD Testing
Shin Yajima, Yuanjia Zhu, Charles J. Stark, Robert J. Wilkerson, Matthew H. Park, Elde Stefan, Y. Joseph Woo, The American Association for Thoracic Surgery
This study aimed to biomechanically evaluate the force profiles on the anterior primary and secondary chordae after neochord repair for anterior valve prolapse with varied degrees of residual mitral regurgitation using an ex vivo heart simulator. Briefly, a 3D printer was used to rapidly develop a prototype of a modular left heart coupled to a pulsatile linear actuator (ViVitro Superpump; ViVitro Labs). In our ex vivo AVP model, moderate residual MR following neochord repair was significantly associated with increased forces for both anterior primary and secondary chordae compared with those of less-than-moderate residual MR.
Other Products Cited: Ex ViVo Simulation Pulsatile Flow Simulation Pulse Duplicator
Visit SourceSofia Di Leonardo, Danila Vella, Carmelo Savio Grillo, Carla Martorana, Salvatore Torre, Vincenzo Argano, Gaetano Burriesci, European Journal of Cardio-Thoracic Surgery, ezad040
This work investigates the impact of the valve-sparing technique on the aortic valve function. The hydrodynamic performance assessment of each implant was conducted in-vitro on a hydro-mechanical pulse duplicator. This shows that, despite providing generally good performance, current valve sparing techniques are still suboptimal and far from matching the physiological leaflets dynamics.
Other Products Cited: Pulse Duplicator
Visit SourceRobert J Melder, Filippo Naso, Francesco Nicotra, Laura Russo, Ivan Vesely, Sugat R Tuladhar, Antonio M Calafiore, Peter Zilla, Alessandro Gandaglia, Sotiris Korossis, European Journal of Cardio-Thoracic Surgery, ezac583
This study was to evaluate the impact of a polyphenols-based treatment on the extrinsic mechanisms responsible for early BHV degeneration. The hydrodynamic performance of the polyphenolic-treated and untreated T-GT commercial BHVs was assessed under simulated pulsatile flow in a Vivitro Pulse Duplicator System. The treatment is chemically stable, improves tissue extensibility, and effectively stabilizes glutaraldehyde.
Other Products Cited: Pulse Duplicator
Visit SourceYuanjia Zhu, Matthew H. Park, Annabel Imbrie-Moore, Robert Wilkerson, Sarah Madira & Y. Joseph Woo, Journal of Cardiothoracic Surgery volume 17, Article number: 303 (2022)
Aortic regurgitation (AR) is one of the most common cardiac valvular diseases, and it is frequently caused by cusp prolapse. The simulator contains a programmable pulsatile linear piston pump (ViVitro Superpump, ViVitro Labs) and a viscoelastic impedance adapter (ViVitro) that is comprised of two compliance chambers and a fixed resistance element and generates a physiologic ventricular waveform. In this study, we successfully designed a commissure geometric alignment device that can manipulate aortic commissure positions to induce aortic cusp prolapse.
Other Products Cited: Pulse Duplicator
Visit SourceFeng Guo, Rizheng Han, Jishan Ying, Zeping Zhang, Rui Yang, Xing Zhang, Journal of Materials Science & Technology, Volume 144, 1 May 2023, Pages 178-187
In this work, bioinspired anisotropic polymeric heart valves were fabricated using composite materials from polyurethane (PU) and natural cellulose fiber bundles. The hydrodynamic performance of the polymeric valve was evaluated by the ViVitro Pulse Duplicator system. Our results demonstrate the potential application of bioinspired anisotropic CPU composites as polymeric heart valves.
Other Products Cited: Pulse Duplicator
Visit SourceLawrence N. Scotten, Rolland Siegel, David J. Blundon, Marcus-André Deutsch, Terence R. P. Martin, James W. Dutton, Ebrahim M. Kolahdouz, Boyce E. Griffith
To demonstrate a clear link between predicted blood shear forces during valve closure and thrombogenicity that explains the thrombogenic difference between tissue and mechanical valves and provides a practical metric to develop and refine prosthetic valve designs for reduced thrombogenicity. Incorporated as Vivitro Systems Inc (VSI), our primary focus was research, design and development of cardiac valve implant devices and on the laboratory test systems required. In 2009, work transitioned into a separate independent research and development enterprise, ViVitro Laboratories Inc. (VLI). The application of unique technology, rapid prototyping and ranking of flow velocity patterns near valve closure optimized experimental valve geometry for reduced thrombus potential compared with control valves.
Other Products Cited: Pulse Duplicator
Visit SourceDavid Meier, MD; Geoffrey W. Payne, MSc, PhD; Leila B. Mostaço-Guidolin, PhD; Rihab Bouchareb, MSc, PhD; Courtney Rich, BASc; Althea Lai, BSc; Andrew G. Chatfield, MB ChB; Mariama Akodad; Hannah Salcudean, MSc; Georg Lutter, MD; Thomas Puehler, MD; Philippe Pibarot, DVM, PhD; Keith B. Allen, MD; Adnan K. Chhatriwalla, MD; Lars Sondergaard, MD; David A. Wood, MD; John G. Webb, MD; Jonathon A. Leipsic, MD; Janarthanan Sathananthan, MPH, MBChB; Stephanie L. Sellers, MSc, PhD, EuroIntervention 2022;17:1-1
To assess the impact of bioprosthetic valve fracture (BVF) timing on long-term transcatheter heart valve (THV) durability. Valve testing was performed in the ViVitro Labs testing facilities (ViVitro Labs Inc, Victoria, Canada). Hydrodynamic testing was performed using a commercially available pulse duplicator (ViVitro Labs Inc, Victoria, Canada), meeting the equipment requirements defined in ISO 5840-3 for pulsatile flow testing (16) (Figure 1A). In this bench study, the ACn and the S3 showed acceptable hydrodynamic performances after AWT to 200M cycles, equivalent to 5 years, irrespective of BVF timing compared to no fracture.
Other Products Cited: HiCycle Durability Tester
Visit SourceLisa Carlson Hanse, Marcell J Tjørnild, Simon G Sørensen, Peter Johansen, Ignacio Lugones, Vibeke E Hjortdal, Interactive CardioVascular and Thoracic Surgery, Volume 35, Issue 4, October 2022, ivac227
We investigated a new surgical technique of trileaflet semilunar valve reconstruction possessing the potential of remaining sufficient and allowing for some growth with the child. Pulsatile flow was produced by a Series piston pump (SuperPump AR; ViVitro Labs, Victoria, Canada), connected to the ventricular chamber. TSVR was achievable in vitro. Hydrodynamic pressure and echocardiographic evaluations demonstrated a sufficient and non-stenotic neo-valve.
Other Products Cited: Pulsatile Flow Simulation SuperPump
Visit SourceDavid Meier, Mariama Akodad, Andrew G. Chatfield, Georg Lutter, Thomas Puehler, Lars Søndergaard, David A. Wood, John G. Webb, Stephanie L. Sellers, and Janarthanan Sathananthan, J Am Coll Cardiol Intv. 2022 Aug, 15 (15) 1532–1539
The aim of this study was to assess the impact of commissural misalignment (CMA) on hydrodynamic function following VIV intervention with the ACURATE neo THV using a bench model. In VIV using the ACURATE neo THV at deep implantation, increasing degree of CMA was associated with THV leaflet interaction with those of the surgical valve and worsening regurgitant fraction. THV leaflet interaction was prevented when there was CA.
Other Products Cited: Pulse Duplicator
Visit SourceK.Yu. Klyshnikov, E.A. Ovcharenko, Yu.A. Kudryavtseva, L.S. Barbarash, RUSSIAN JOURNAL OF TRANSPLANTOLOGY AND ARTIFICIAL ORGANS, Vol. XXII, No 2–2020
The aim of the study was an in vitro hydrodynamic study of the developed prosthetic heart valve of the second generation, designed to carry out an implantation using “valve-in-valve” method. ...Prototypes of the developed prosthesis were studied under simulated physiological conditions of the heart using a Vivitro Labs pulse duplicator (Canada) in a comparative aspect with “UniLine” clinical commercial aortic valve bioprosthesis (Russia)... ...The design of the prosthesis under development has shown its consistency in terms of functional characteristics, both in comparison with the original UniLine prosthesis and with literature data....
Other Products Cited: Pulse Duplicator
Visit SourceLibby H. Welborn, Anna K. Himes, Ida E. Greenlee, Nyna J. DeWitt, Ava T. Burgess, Brandon K. Eberl, Olga Pierrakos, 2022 Systems and Information Engineering Design Symposium (SIEDS)
The aim of this paper is to: 1) showcase the design process of a quadleaflet ePTFE valved conduit with a diameter of 16mm or less and 2) offer a hemodynamic performance comparison. ...The proposed valve was tested using the ViVitro Pulse Duplicator under physiologic cardiac conditions... ...A comparison between the two ePTFE handmade valves (trileaflet and quadleaflet) demonstrated hemodynamic differences in regurgitation due to leaflet number. The handmade valves both showed increased regurgitation compared to a Carbomedics valve (commercially available design). Regurgitation had varying effects on pressure gradients and cardiac output...
Other Products Cited: Pulse Duplicator
Visit SourceH. Appa, K. Park, D. Bezuidenhout, B. van Breda, B. de Jongh, J. de Villiers, R. Chacko, J. Scherman, C. Ofoegbu, J. Swanevelder, M. Cousins, P. Human, R. Smith, F. Vogt, B, K. Podesser, C. Schmitz, L. Conradi, H. Treede, H. Schröfel, T. Fischlein, M. Grabenwöger, X. Luo, H. Coombes, S. Matskeplishvili, D. F. Williams, P. Zilla, Front. Cardiovasc. Med., 03 March 2022
...Hydrodynamic testing to determine gradients (ΔP), effective orifice areas (EOA) and regurgitant fractions was performed in a pulse duplicator (Cardiac Output: 5 L/min; 37°C; 70 bpm; Stroke Volume: 32 ± 5 ml; Systolic Phase Duration of 35 ± 5%) (ViVitro Labs Inc; Victoria, BC, Canada)...The BE TAVR system met all requirements for which it was developed...
Other Products Cited: Pulse Duplicator
Visit SourceM. Alizadeh, M. Cote, A. Branzan Albu, Proceedings of the IEEE/CVF Winter Conference on Applications of Computer Vision 2022
...Our experimental setup to collect high-quality videos and pressure and velocity data involves tricupsid BHVs mounted in the Pulse Duplicator device from ViVitro Labs...Experiments on four cases that include three different tricuspid BHVs yielded promising results, with the DTW scores showing a good coherence with respect to the simulations...
Other Products Cited: Pulse Duplicator
Visit SourceB. Ncho, A. Siefert, V. Sadri, J. Ortner, A. Yoganathan. Journal or Med. Devices
The physiologic pressures and flows were achieved by adjustment of systemic resistance and compliance elements, and flow driven from a piston pump (Vivitro Labs Inc. Victoria, Canada).
Other Products Cited: Flow Visualization SuperPump
Visit SourceC. D. Hsu, A. Mirza, R. Matheny, S. Ramaswamy. Structural Heart. Vol. 5.
...hydrodynamic testing of the valves mounted in mitral and tricuspid positions were performed using a pulse duplicator system (ViVitro Labs) using 0.9% saline solution...
Other Products Cited: Pulse Duplicator
Visit SourceJae H. Lee, Alex D. Rygg, Ebrahim M. Kolahdouz, Simone Rossi, Stephen M. Retta, Nandini Duraiswamy, Lawrence N. Scotten, Brent A. Craven, and Boyce E. Grith -
Computer modeling and simulation (CM&S) is a powerful tool for assessing the performance of medical devices such as bioprosthetic heart valves (BHVs) and promises to accelerate device design and regulation. This study describes work to develop dynamic computer models of BHVs in the aortic test section of an experimental pulse duplicator platform that is used in academia, industry, and regulatory agencies to assess BHV performance... ...This work represents a step towards the experimental validation of this FSI modeling platform for evaluating BHVs.... … In vitro experiments are performed using two different experimental platforms, including a ViVitro Pulse Duplicator (ViVitro Labs, Inc., Victoria, BC, Canada) available through the FDA Cardiac Device Flow Lab and a customized …
Other Products Cited: Pulsatile Flow Simulation Pulse Duplicator
Visit SourceFeng Guo (郭峰)Chang Liu (刘唱)Rizheng Han (韩日峥)Qiang Lu (吕强)Yun Bai (白芸)Rui Yang (杨锐)Dun Niu (牛盾)Email authorXing Zhang (张兴) -Science China Materials
Herein, two types of silk fibroin (SF) fiber membranes with anisotropic (ASF) and isotropic (ISF) properties were prepared by electrospinning, and were further combined with poly(ethylene glycol) diacrylate (PEGDA) hydrogels to serve as polymeric heart valve (PHV) substitutes (PEGDA-ASF and PEGDA-ISF)... ...The PHVs from both PEGDA-ASF and PEGDA-ISF presented appropriate hydrodynamic properties from pulse duplicator tests according to the ISO 5840-3 standard.... ...The Gauss curvature analysis also indicated that the anisotropic PEGDA-ASF valve can produce appropriate surface morphology by dynamically adjusting the movement of bending area during the opening process... … 1c, d). Pulse duplicator tests In vitro hemodynamic properties of PHVs were tested in a 0.9% saline solution using a pulse duplicator system (Vivitro Labs, Inc., British Columbia, Canada) according to the ISO 5840-3 standard [21] …
Other Products Cited: Pulse Duplicator
Visit SourceMiss Brittany A. Gonzalez, Miss Elnaz Pour Issa, Mr. Omkar V. Mankame, Miss Jenniffer Bustillos, Mr. Antonio Cuellar, Mr. Andres J. Rodriguez, Dr. Frank Scholl, Dr. Steven Bibevski, Dr. Lazaro Hernandez, Mr. Vincent Brehier, Mr. Mike Casares, Dr. Krishna Rivas, Dr. Pablo Morales, Mr. Jesus Lopez, Dr. Joseph Wagner, Dr. Jennifer Bibevski, Dr. Arvind Agarwal, Dr. Florence George, and Dr. Sharan Ramaswamy - Tissue Engineering Part A. December 5, 2019
Conceptually, a tissue engineered heart valve (TEHV) would be especially appealing in the pediatric setting since small size and somatic growth constraints would be alleviated. Here, we utilized porcine small intestinal submucosa (PSIS) for valve replacement... … the Dacron tubes housing the PSIS valves were measured in order to secure the valve‐in‐ conduit (Figure 1) in the mitral position within a pulse duplicator system (ViVitro Labs, Victoria, BC) … A pulse duplicator system… ... Our findings suggest that the altered structural responses of PSIS, post-fatigue, rather than de novo tissue formation, are primarily responsible for the valve’s ability to accommodate somatic growth during the acute phase (90 days) following mitral valve replacement...
Other Products Cited: Pulse Duplicator Tissue Engineering
Visit SourceJae H. Lee, Alex D. Rygg, Ebrahim M. Kolahdouz, Simone Rossi, Stephen M. Retta, Nandini Duraiswamy, Lawrence N. Scotten, Brent A. Craven, and Boyce E. Grith - ResearchGate 2019
This study describes work to develop dynamic computer models of BHVs in the aortic test section of an experimental pulse duplicator platform... ...We compare our numerical simulations to experimental data from two similar pulse duplicators, including a commercial ViVitro system and a custom platform related to the ViVitro pulse duplicator.... ...This work represents a step towards the experimental validation of this FSI modeling platform for evaluating BHVs....
Other Products Cited: Pulse Duplicator
Visit SourceAmanda Barreto,Asad M. Mirza, Daniel Chaparro, Ahmed Z. Ali, Rachel Montlavan, Joshua D. Hutcheson, Sharan Ramaswamy - FIU Digital Commons
... Aortic valve calcification (AVC) is caused by defects in the valves and it is a health condition which usually requires surgical valve replacement... ...The proposed project aims to capture images of the aortic leaflet curvature while cyclic flexure is conducted... The curvature of the leaflets will be captured using two high-frame rate video systems. The aortic valve leaflet flexure experiments will be produced using a Vivitro Pulse Duplicator (Vivitro Labs Inc. Victoria, BC, Canada) …
Other Products Cited: Pulse Duplicator
Visit Source