Articles Related to Pulse Duplicator

A. Desai, T. Vafaee, P. Rooney, J.N. Kearney, H.E. Berry, E. Ingham, J. Fisher, L.M. Jennings Journal of the Mechanical Behavior of Biomedical Materials 14 September 2017

The use of decellularised biological heart valves in the replacement of damaged heart valves ... ...The purpose of this study was to assess the effect of low concentration sodium dodecyl sulphate decellularisation on the in vitro biomechanical and hydrodynamic properties of cryopreserved human aortic and pulmonary roots.... ... performance of the valve roots. A viscoelastic impedance adapter (VIA; Vivitro System Inc., Victoria BC, Canada) was used to deliver a more physiological ventricle pressure and flow waveform in the simulator. This system allowed for ...

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Retta SM, Kepner J, Marquez S, Herman BA, S Shu MC, Grossman LW J Heart Valve Dis. 2017 Jan;26(1):72-80.

One of the first steps in qualifying a new prosthetic valve for eventual clinical use is preclinical flow performance testing in vitro... ...This collaborative effort between heart valve manufacturers and the Food and Drug Administration (FDA) was designed to evaluate the variability of the pulse duplicator test technology for pulsatile flow performance measurement in an interlaboratory round robin... ...A commercially available duplicator, the Vivitro system (Vivitro, Inc., Vancouver, Canada), was used at two centers. The design specifications are summarized in Table I....

Other Products Cited:  Heart Valve Testing

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Yen Ngoc NguyenMunirah IsmailFoad KabinejadianChi Wei OngEdgar Lik Wui TayHwa Liang Leo - Cardiovascular Engineering and Technology 2017

The increased understanding of right heart diseases has led to more aggressive interventions to manage functional tricuspid regurgitation (FTR)... ...In this study, a novel in vitro mock circulatory system that incorporated a realistic tricuspid valve apparatus in a patient-specific silicon right ventricle (RV) was designed and fabricated... ... A closed ventricular chamber housing the silicon RV model was connected to a closed atrial chamber at one end, and was directly connected to the pulsatile wave-generating piston pump (SuperPump AR series, ViVitro Labs Inc., Victoria, BC, Canada) at the other end to simu ...

Other Products Cited:  Heart Valve Testing

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Guangyu Zhu; Masakazu Nakao; Qi Yuan and Joon Hock Yeo Proceedings of the 10th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 1: BIODEVICES, 186-189, 2017, Porto, Portugal

Truly stentless polymeric valve prosthesis can be a viable alternative for aortic valve replacement (AVR). In the present paper, the dynamic and hemodynamic performance of a novel designed expanded-polytetrafluoroethylene (ePTFE) stentless tri-leaflet valve was assessed experimentally.... ... The in-vitro tests were performed under time-varying physiological pressure by using the Vivitro pulse duplicator. ... The Vivitro pulse duplicator (Vivitro Systems Inc., Victoria, BC, Canada) was used to generate the physiological pressure and flow in the left ventricle and aorta. ...

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M. Alizadeh, M. Cote, and A Branzan Albu P Sharma, FM Bianchi - Image Analysis 20th Scandinavian Conference, SCIA 2017,

...The valve orifi ce area over time, which informs on the opening and closing motion patterns, constitutes a key quality metric for PHV assessment... ...In this paper, we propose a novel orifi ce segmentation approach for automatic prosthetic heart valves quantitative performance analysis, based on the detection of the leaflet free edges to accurately extract the actual orifi ce area.

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Ng, Daniel Wai Hung. Neo, Si Yang. Ng, Chung Liu. Wong, Benedict Jun Shuan. Singapore Polytechnic School of Mechanical & Aeronautical Engineering

...Mechanical valves usually made from metal and fabrics are very durable but they have poor hemodynamic and are thrombogenic requiring permanent anticoagulation. Tissue heart valves constructed from biological tissues have excellent hemodynamic blood flow, but they lack durability. The project proposed a new valve design that is similar to a stentless tissue valve but made from a synthetic material, Polytetrafluoroethylene (PTFE)... The scope of this project includes designing a fixture to accommodate the valves in the ViVitro System and studying hemodynamic parameters such as pressure drop, flow rate, and dynamic leaflet behaviour of the valves. ...

Other Products Cited:  Heart Valve Testing

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Andrew K. Capullia, Maximillian Y. Emmerta, b, c, Francesco S. Pasqualinia, b, Debora Kehlb, Etem Caliskanb, c, Johan U. Linda, Sean P. Sheehya, Sung Jin Parka, Seungkuk Ahna, Benedikt Webera, b, Josue A. Gossa, Simon P. Hoerstrupa, b, Kevin Kit Parkera; Biomaterials Volume 133, July 2017, Pages 229–241

Tissue engineered scaffolds have emerged as a promising solution for heart valve replacement because of their potential for regeneration. However, traditional heart valve tissue engineering has relied on resource-intensive, cell-based manufacturing, which increases cost and hinders clinical translation. ...We demonstrated controlled modulation of these scaffold parameters and show initial biocompatibility and functionality in vitro...

Other Products Cited:  Tissue Engineering

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Bozkurt, S., Preston-Maher, G.L., Torii, R. et al. Ann Biomed Eng (2017). doi:10.1007/s10439-017-1828-2 First Online: 03 April 2017

Mitral regurgitation is a common mitral valve dysfunction which may lead to heart failure. This paper presents the design, development and hydrodynamic assessment of a novel bi-leaflet mitral valve suitable for transcatheter implantation. ... animal models. Hydrodynamic Tests. The hydrodynamic performances of the three valve prototypes were assessed on a hydro-mechanical cardiovascular pulse duplicator system (ViVitro Superpump SP3891, ViVitro, BC) (Fig. 3 ...

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Wentao Feng, Xianda Yang, Yang Liu, Yubo Fan Artificial Organs, 24 February 2017

Clinically, the percutaneous transcatheter aortic valve (TAV) has been reported to be deformed in a noncircular configuration after its implant. The deformation is universal and various, and it leads to serious leakage and durability problems. ...the present study investigated the effects of the aortic annulus deformation and the leaflet tissue thickness on the hydrodynamics of the TAV. ... Hydrodynamic testing. The TAVs were tested in a quasi-physiological artery pulsatile flow duplicator system, which was custom remoulded to adapt the testing of deformed TAV from commercially available pulse duplicator (Pulse Duplicator; Vivitro Labs, Victoria, BC, Canada.). ...

Other Products Cited:  Heart Valve Testing

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Sharan Ramaswamy, Makensley Lordeus, Omkar V. Mankame, Lilliam Valdes-Cruz, Steven Bibevski, Sarah M. Bell, Ivan Baez, Frank Scholl: Cardiovasc Eng Tech (2016).

...Assess the functional effectiveness of tri-leaflet PSIS bioscaffolds in the aortic position compared to standard tri-leaflet porcine bioprosthetic valves... ... (b) Pulse duplicator system (Vivitro Laboratories) used for the hydrodynamic evaluation of the valves. ... System calibration, pump control, data collection and analysis are all computer-controlled via software (Vivitest, Vivitro Labs). ...

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