Articles Related to Applications

Filippo Piatti1 , Francesco Sturla 1,2 , Thomas E. Claiborne3 , Danny Bluestein3 , Alberto Redaelli 1

Experimental procedures are commonly used to obtain an overall quantification of the fluid dynamic and thrombogenic performances of cardiovascular devices [1]... (B) ViVitro gold standard testing benchmark (ViVitro Labs, BC, Canada) Boundary conditions ... obtaining comparable working conditions between the computational model and the ViVitro benchmark. Figure 2 – Schematic visualization of the ideal ...

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Hadi Daood Toeg, Ovais Abessi , Talal Al-Atassi, Laurent de Kerchove, Gebrine El-Khoury, Michel Labrosse, Munir Boodhwani, - Cardiovasc Surg, 2014

ABSTRACT Aortic valve (AV) repair (AVr) has become an attractive alternative to AV replacement for the correction of aortic insufficiency; however, little clinical evidence exists in determining which biomaterial at AVr would be optimal. Cusp replacement in AVr has... All aortic roots were connected to the ViVitro Left Heart Simulator (LHS; ViVitro Systems, Inc, Victoria, British Columbia, Canada) for baseline valve measurements acting as paired controls...

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E Frankowska, Z Trawi; Poster No.: C-0473 Congress: ECR 2014 Type: Scientific Exhibit

... Model of the LV was made from solution of POLY(VINYL ALCOHOL). Pulsatile filling of the LV phantom was driven by automatic and computer controlled hydraulic piston pump (Vivitro Inc., Canada) with stroke volume of 20 ml and the frequency of 60 impactions per minute. ...

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A Falahatpisheh, G Pedrizzetti, A Kheradvar; Experiments in Fluids November 2014, 55:1848

... We used a heart-flow simulator consisting of a hydraulic pump system (Superpump system, VSI, SPS3891, Vivitro systems Inc., Victoria, BC, Canada) that operates based on a VSI Wave Generator VG2001 (Vivitro Systems Incorporated, Victoria, BC, Canada), as previously ...

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Z Trawiński, J Wójcik, A Nowicki, A Balcerzak…

... Our model of the LV was driven by the computer-controlled hydraulic piston Super-Pump (Vivitro Inc., Canada) with adjustable fluid volumes. ... The data were reconstructed every 10% of the R-to-R interval of the ECG signal produced by the Vivitro SuperPump control device. ...

Other Products Cited:  Pulsatile Flow Simulation  SuperPump  Ultrasound Measurements

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Azadani AN1, Jaussaud N, Matthews PB, Ge L, Chuter TA, Tseng EE., Interact Cardiovasc Thorac Surg. 2010 Jul;11(1):70-7. doi: 10.1510/icvts.2009.225144. Epub 2010 Apr 15.

Transcatheter aortic valves (TAVs) are a promising treatment for high risk surgical patients suffering from degeneration of previously implanted bioprostheses (valve-in-valve therapy).

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Francis Robicsek, MD, PhD, Mano J Thubrikar, PhD, American Journal of Cardiology Volume 84, Issue 8, Pages 944–946, October 15, 1999

Functional morphology of the normal aortic root was studied in vitro using 500 frames/s cinematography. Stiffening of the aortic wall by spraying its exterior with plastic adhesive led to compromised function of the leaflets...

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Francis Robicsek MD, PhD, Mano J. Thubrikar PhDb, Joseph W. Cook MDa and Brett Fowler RTb; The Annals of Thoracic Surgery: 77, Issue 1; 177-185.

The study was intended to investigate the reason why congenitally bicuspid valves (CBAVs), which may function hemodynamically and clinically well, have a high early failure rate.

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George P. Chatzimavroudis, PhD, John N. Oshinski, PhD, Roderic I. Pettigrew, MD, PhD, Peter G. Walker, PhD, Robert H. Franch, MD, Ajit P. Yoganathan, PhD; Journal of Magnetic Resonance Imaging: 8, Issue 3; 577 – 582.

Reliable diagnosis and quantification of mitral regurgitation are important for patient management and for optimizing the time for surgery. Previous methods have often provided suboptimal results. The aim of this in vitro study was to evaluate MR phase-velocity mapping in quantifying the mitral regurgitant volume (MRV) using a control volume (CV) method.

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W.Lim; Journal of Biomechanics: 34, Issue 11; 1417-1427.

A two-dimensional particle image tracking velocimetry (PIV) system has been used to map the velocity vector fields and Reynolds stresses in the immediate downstream vicinity of a porcine bioprosthetic heart valve at the aortic root region in vitro under pulsatile flow conditions. Measurements were performed at five different time steps...

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M. Nobili, U. Morbiducci, R. Ponzini, C. Del Gaudio, A. Balducci, M. Grigioni, F. Maria Montevecchi, A. Redaelli; Journal of Biomechanics: 41, Issue 11; 2539-2550.

The main purpose of this study is to reproduce in silico the dynamics of a bileaflet mechanical heart valve (MHV; St Jude Hemodynamic Plus, 27mm characteristic size) by means of a fully implicit fluid-structure interaction (FSI) method, and experimentally validate the results using an ultrafast cinematographic technique.

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Scotten LN**, Walker DK**, Dutton JW; Journal of Heart Valve Disease: 11, Issue 3; 368  **ViVitro Labs Founder

The accuracy of the Gorlin equation when applied to mixed valve pathology has not been investigated. An in-vitro study was performed to determine how a range of valve regurgitations and stenoses affects the Gorlin aortic valve area...

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Simcha Milo, Edmond Rambodb, Chaim Gutfingerc and Morteza Gharibb; European Journal of Cardio-Thoracic Surgery: 24, Issue 3; 364-370.

The goal of the present work was to create the closest possible in vitro fluid dynamic environment in which prosthetic mitral valves in the patients' hearts function, in order to demonstrate whether microbubbles are generated, and if yes, under what conditions and at which stage of the cardiac cycle...

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Poulsen, J.K. Kim, W.Y; IEEE Transactions on Biomedical Engineering: 43, Issue 6; 589-599.

In this paper we show that by scanning at points on the surface of a sphere that the normal angle correction used in pulsed Doppler flow measurements is no longer necessary.

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Brant H. Maines, Christopher E. Brennen; Journal of Biomechanical Engineering: 127, Issue 4; 648.

The cavitation inception threshold of mechanical heart valves has been shown to be highly variable. This is in part due to the random distribution of the initial and final conditions that characterize leaflet closure.

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M. Labrosse, C. Beller, F. Robicsek, M. Thubrikar; Journal of Biomechanics: 39, Issue 14; 2665-2672.

The dimensions of the aortic valve components condition its ability to prevent blood from flowing back into the heart. While the theoretical parameters for best trileaflet valve performance have already been established, an effective approach to describe other less optimal, but functional models has been lacking...

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J. Timothy Baldwin*, Andy Campbell, Christopher Luck, William Ogilvie and Joe Sauter; European Journal of Cardio-Thoracic Surgery: 11, Issue 2; 287-292.

To compare hydrodynamic characteristics of a new bileaflet heart valve, the CarboMedics kinetic cardiac valve prosthesis, with those of a St. Jude Medical (SJM) heart valve...

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G. Tansley, S. Vidakovic, and J. Reizes; Artificial Organs: 24, Issue 6; 483 – 487.

The VentrAssist pump has no shaft or seal, and the device is unique in design because the rotor is suspended passively by hydrodynamic forces, and urging is accomplished by an integrated direct current motor rotor that also acts as the pump impeller. This device has led to many challenges in its fluidic design...

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Peacock J, Hankins S, Jones T, Lutz R. Journal of Biomechanics: 28, Issue 1; 17-26.

An in vitro pulse duplicator system was used to investigate whether coronary artery stents induce downstream flow instabilities. Hot film or electrochemical probes were used to measure wall shear stress before and after deployment of both single and multiple (overlapping) stents in normal and diseased coronary geometries...

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Daniel Zimpfer MDa, Heinz Schima PhDb, Martin Czerny MDa, Marie-Theres Kasimir MDa, Sigrid Sandner MDa, Gernot Seebacher MDa, Udo Losert PhDc, Paul Simon MDa, Michael Grimm MDa, Ernst Wolner MD, PhDa and Marek Ehrlich MD; The Annals of Thoracic Surgery: 85, Issue 2; 470-473.

BACKGROUND: This study assessed the feasibility of stent graft treatment of ascending aortic dissections in a porcine in vitro model. METHODS: The entire thoracic aortic aorta including the supraaortic branches was harvested from 12 adult pigs and an intimal tear was artificially created. ...

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