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Ahmad Falahatpisheha, Daisuke Morisawaa, Taraz T. Tooskyb, Arash Kheradvara Journal of Biomechanics Available online 16 November 2016
...developed a novel polymeric valve whose leaflets possess calcium hydroxyapatite inclusions immersed in them. This study reports the characteristics and feasibility of these valves. ... The system is connected and actuated by a pulsatile pump system (Superpump system, VSI, SPS3891, Vivitro systems Inc., Victoria, BC, Canada), which operates based on a VSI Wave Generator VG2001 (Vivitro Systems Inc., Victoria, BC, Canada) and controlled by a ...
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Visit SourceKeyvan Amini Khoiy, Dipankar Biswas, Thomas N Decker, Kourosh T Asgarian, Francis Loth and Rouzbeh Amini Circulation November 11, 2016, Volume 134, Issue Suppl 1
...study to establish a framework for the measurement of the deformation of TV leaflets in a passive ex-vivo beating heart that mimicked the right ventricular dynamic pressure of the normal hearts. ...apexes of fresh porcine hearts (n= 8) were connected to a positive displacement pump (SuperPump AR Series, Vivitro Labs Inc., BC) to generate pulsatile flow in the right side of the hearts. The superior vena cava was connected to a reservoir as the inflow pathway and the pulmonary artery was used for the outflow pathway...
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Visit SourceE. Foucaulta, S. Hubersona, P. Brauda, D. Coisneb European Journal of Mechanics-B/Fluids Available online 17 November 2016
...study investigates pulsatile flow through models of junctions corresponding to geometries most usually observed in the major coronary artery, with and without stent. ... 31] and [32]. 2.2. Experimental setup. The mean flow has its source in a tank set at constant height, the oscillatory flow is driven by a piston pump (Model SPS 3891,Vivitro Systems, Canada) as shown in Fig. 1. The oscillatory ...
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Visit SourceEsmé J. Donselaar, MD, Andrew Holden, FRANZCR, EBIR, Aleksandra C. Zoethout, BSc, Clark J. Zeebregts, MD, PhD, Michel M. P. J. Reijnen, MD, PhD Journal of Endovascular Therapy Nov 17, 2016
Purpose: To describe the feasibility and technical aspects of a proximal Nellix-in-Nellix extension to treat caudal stent-graft migration after endovascular aneurysm sealing (EVAS) in the in vitro and in vivo settings. ... Silicone anatomical models were used in conjunction with a pulsatile flow pump (SuperPump; Vivitro Labs Inc, Victoria, British Columbia, Canada). The system was tuned to a pressure of ~120/80 mm Hg, with 4.5- to 5-L/min flow at a rate of 70 beats/min. ...
Other Products Cited: Endovascular Simulator
Visit SourceKeyvan Amini Khoiy, Dipankar Biswas, Thomas N. Decker, Kourosh T. Asgarian, Francis Loth and Rouzbeh Amini; Journal of Biomechanical Engineering revised August 23, 2016
...For the first time, the porcine valve leaflets deformation was measured in a passive ex-vivo beating heart without isolating and remounting the valve annuli. In particular, the right ventricular apexes of porcine hearts (n = 8) were connected to a pulse-duplicator pump that maintained a pulsatile flow from and to a reservoir connected to the right atrium and the pulmonary arteries... A positive displacement pump 116 (SuperPump AR Series, Vivitro Labs Inc., BC, Canada) was connected to the apex of the right 117 ventricle after an incision was carefully made at this location (as described in more detail below)...
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Visit SourceMunirah Ismail, Gideon Praveen Kumar, Foad Kabinejadian, Yen Ngoc Nguyen, Fangsen Cui, Edgar Lik Wui Tay, Hwa Liang Leo - Cardiovascular Engineering and Technology pp 1-16 First online: 29 June 2016
Transcatheter tricuspid valves are implanted onto the cavoatrial junction in order to avoid the challenging task of anchoring the valve onto the complex tricuspid valve annulus. ...little is known about optimum extent of oversizing of the valved stent in a vena cava. In this study, we implanted valves of the same diameter onto the larger sized inferior vena cava (IVC) and a smaller sized superior vena cava (SVC). ... that half of the valve protrudes out of the vena cava. This is to comply with the anatomical constraint of not occluding the hepatic vein. The pulsatile flow loop was driven by a wave-generating piston pump (SuperPump AR series, ViVitro Labs Inc., Victoria, BC, Canada). ...
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Visit SourceSean Guo-Dong Tan, Sangho Kim, Hwa Liang Leo Experiments in Fluids June 2016, 57:110
Mechanical heart valve prostheses are often implanted in young patients due to their durability and long-term reliability. However, existing designs are known to induce elevated levels of blood damage and blood platelet activation... ...This study proposes a bi-leaflet mechanical heart valve design (Bio-MHV) that mimics the geometry of a human mitral valve, with the aim of reducing turbulence levels in the left ventricle by replicating physiological flow patterns... ... A pulsatile pump (ViVitro Labs Inc., Victoria, BC) attached to the working chamber drove the blood analog around the flow loop, via the pumping action of the silicon left ventricle, as shown in Fig. 1c. Fig. 2 a A mitral flow waveform sample observed in the experiments. ...
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Visit SourceJohn Davidson, Sangjin Ryu Journal of Visualization pp 1-9 First online: 30 May 2016
Soap bubble blowing has long been an amusement for humans, and the process involves pinch-off similarly to liquid drops and gas bubbles. ... 2.4.2 Measurement using a Pitot tube. To validate the image-based speed measurement, we measured the airflow speed at the center of the nozzle outlet (U e ) using a Pitot static tube (PAA-8-KL, United Sensor Corp.) with pressure transducers (Pulse Duplicator, ViVitro Labs). ...
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Visit SourceBernhard M. Vennemann , Thomas Rösgen, Thierry P. Carrel, Dominik Obrist - Article Cardiovascular Engineering and Technology pp 1-13 First online: 13 May 2016
The Lapeyre-Triflo FURTIVA valve aims at combining the favorable hemodynamics of bioprosthetic heart valves with the durability of mechanical heart valves (MHVs). ... physiological con- ditions. It is driven by a peristaltic pump (Superpump, Vivitro Systems, Victoria, BC, Canada) (1) which generates a directed pulsatile flow through the test section (3). The net flow through the transparent test section is ...
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Visit SourceGuo-Dong Sean Tan and Hwa Liang Leo - J. Med. Devices 10(2), 020910 (May 12, 2016) (3 pages)
... physiological conditions. It is driven by a peristaltic pump (Superpump, Vivitro Systems, Victoria, BC, Canada) (1) which generates a directed pulsatile flow through the test section (3). The net flow through the transparent test section is ...
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Visit SourceSimon Heide-Jørgensen, Sellaswasmy Kumaran Krishna, Jonas Taborsky, Tommy Bechsgaard, Rachid Zegdi and Peter Johansen J Biomech Eng 138(3), 034504 (Jan 29, 2016) (7 pages)
The aim of this study was to develop a platform for noncontact TAVI valve deformation analysis with both high temporal and spatial resolutions based on stereophotogrammetry and digital image correlation (DIC). A left-heart pulsatile in vitro flow loop system for mounting of TAVI valves was designed. ... Based on a piston pump (ViVitro SuperDup'r pump, ViVitro systems, Victoria, BC, Canada) a left-heart in vitro flow loop with peripheral units comprising a ventricular chamber, an atrial reservoir, an aortic root in which test valves can be installed, an arterial compliance section ...
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Visit SourceMorgane Evin, Carine Guivier-Curien, Philippe Pibarot, Lyes Kadem and Régis Rieu
... Jude Medical size 23 mm, a resistance and a compliance). The BMHV to be tested is placed directly between the left atrium and the left ventricle molds. The activation of the left ventricle is performed by a Vivitro superpump (VivitroLabs, Victoria, BC, Canada). ...
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Visit SourceErwan Salauna, Anne-Sophie Zensesb, Morgane Evinb, Frédéric Collartd, Gilbert Habiba, Philippe Pibarote, Régis Rieub International Journal of Cardiology Available online 8 January 2016
This in-vitro study aims to assess and compare the valve hemodynamic performances of the Edwards SAPIEN transcatheter heart valve (THV) in the different current conditions of use: important oversizing in small circular annuli and in elliptical annuli, moderate oversizing in circular and in elliptical annuli of various degrees of eccentricity.
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Visit SourceIkechukwu Okafor, Arvind Santhanakrishnan, Vrishank Raghav, Ajit Yoganathan- Journal of Biomechanical Engineering 10/2015;
...The results support the hypothesis that a D-shaped mitral annulus reduces dissipative energy losses in ventricular filling during diastole, and in turn suggests that a symmetric stent design does not provide lower filling efficiency than an equivalent asymmetric design. ...fluctuations were imposed in a fluid-filled chamber housing the LV physical model using a programmable piston pump (Superpump, Vivitro Systems; British Columbia, Canada). The pressure fluctuations resulted in the deformation of the LV model, driving flow through ...
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Visit SourceZeeshan Syedaina, Jay Reimera, Jillian Schmidta, Matthew Lahtic, James Berryc, Richard Biancoc, Robert T. Tranquillo - doi:10.1016/j.biomaterials.2015.09.016
Diseased aortic valves often require replacement, with over 30% of the current aortic valve surgeries performed in patients who will outlive a bioprosthetic valve. While many promising tissue-engineered valves have been created in the lab using the cell-seeded polymeric scaffold paradigm, none have been successfully tested long-term in the aortic position of pre-clinical model. ... A customized pulse duplicator system was designed based on a commercial wave generator and pump (ViVitro Systems). ...
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Visit SourceAndrea Salicaa, Giuseppe Pisanib, Umberto Morbiduccib, Raffaele Scaffaa, Diana Massaib, Alberto Audeninob, Luca Welterta, Lorenzo Guerrieri Wolfa and Ruggero De Paulisa - - European Journal of Cardio- Thoracic Surgery (2015), First published online: September 10, 2015
Normal aortic valve opening and closing movement is a complex mechanism mainly regulated by the blood flow characteristics and the cyclic modifications of the aortic root. Our previous in vitro observations demonstrated that the presence of the Valsalva sinuses, independently from root compliance, is important in reducing systolic pressure drop across the aortic valve. ... The hydrodynamic performances under pulsatile flow regimen were investigated, using a Vivitro System, Inc. ... Direct visualization of valve operating condition was performed, using an ultrafast speed camera (Casio Exlim Ex F1), mounted on top of the Vivitro system [19, 20]. ...
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Visit SourceJahren, Silje Ekroll; Heinisch, Paul Philipp; Wirz, Jessica; Winkler, Bernhard; Carrel, Thierry; Obrist, Dominik (31 March 2015). Hemodynamic Performance of Edwards Intuity Valve in a Compliant Aortic Root Model (In Press). In: IEEE EMBC 2015. Milano. 25.08.-29.08.2015.
...It was the aim of this study to perform hemodynamic and kinematic measurements for this type of valves to serve as a baseline for following studies which investigate the effect of the aortic root on the valve performance. To this end, the Edwards Intuity aortic valve was investigated in a new in vitro flow loop mimicking the left heart...
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Visit SourceBernhard Vennemann, David Hasler, Silje E. Jahren, Thomas Rösgen, Thierry P. Carrel, Dominik Obrist - Heart Valve Society 1st Annual Meeting MAY 6-9, MONTE CARLO, MONACO, GRIMALDI FORUM
...so called hot spots, where activated platelets might aggregate and form a thrombus that can ultimately lead to leaflet blockage. It is the aim of this study to assess the hemodynamics in the pivoting area of the Triflo valve.
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Visit SourceIkechukwu U. Okafor, Arvind Santhanakrishnan, Brandon D. Chaffins, Lucia Mirabella, John N. Oshinski and Ajit P. Yoganathan - Journal of Cardiovascular Magnetic Resonance 2015, 17:51 doi:10.1186/s12968-015-0154-9
... A programmable piston pump (PPP; Vivitro Systems Inc., Victoria, Canada) was used to induce the LV wall motion by altering the pressure of the fluid in the space between the interior of acrylic chamber housing the LV model and the exterior of the LV model. ...
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Visit SourceClara Seaman, Andrew McNally, Stephen Biddle, Lauren Jankowski, Philippe Sucosky Presented in part at the 2013 Biomedical Engineering Society Conference, September 2013, Seattle, WA, and at the 2013 ASME Summer Bioengineering Conference, June 2013, Sunriver, OR, USA
The study aim was to develop a laboratory protocol for the fabrication of tissue valve models mimicking mild and moderate calcific stenosis, for future use in flow studies. ... near-physiologic hemodynamics. The flow loop was driven by a programmable piston pump (Vivitro), and included resistance and compliance units to mimic the characteristics of the systemic vascular tree (Fig. 3A). The system ...
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