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M. Alizadeh, M. Cote, and A Branzan Albu P Sharma, FM Bianchi - Image Analysis 20th Scandinavian Conference, SCIA 2017,
...The valve orifi ce area over time, which informs on the opening and closing motion patterns, constitutes a key quality metric for PHV assessment... ...In this paper, we propose a novel orifi ce segmentation approach for automatic prosthetic heart valves quantitative performance analysis, based on the detection of the leaflet free edges to accurately extract the actual orifi ce area.
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Visit SourceRiccardo Toninatoa, Jacob Salmona, Francesca Maria Susin, Andrea Duccia, Gaetano Burriescia doi:10.1016/j.jbiomech.2016.05.027
The physiological flow dynamics within the Valsalva sinuses, in terms of global and local parameters, are still not fully understood. This study attempts to identify the physiological conditions as closely as possible, and to give an explanation of the different and sometime contradictory results in literature. ... 2. Material and Methods. In this study, all experiments were carried out using a hydro-mechanical pulse duplicator (Vivitro Superpump System SP3891, ViVitro Labs Inc., Canada), with pressure catheters monitoring the pressure upstream and downstream of the aortic valve. ...
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Visit SourceJahren, Silje Ekroll; Heinisch, Paul Philipp; Wirz, Jessica; Winkler, Bernhard; Carrel, Thierry; Obrist, Dominik (31 March 2015). Hemodynamic Performance of Edwards Intuity Valve in a Compliant Aortic Root Model (In Press). In: IEEE EMBC 2015. Milano. 25.08.-29.08.2015.
...It was the aim of this study to perform hemodynamic and kinematic measurements for this type of valves to serve as a baseline for following studies which investigate the effect of the aortic root on the valve performance. To this end, the Edwards Intuity aortic valve was investigated in a new in vitro flow loop mimicking the left heart...
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Visit SourceBernhard Vennemann, David Hasler, Silje E. Jahren, Thomas Rösgen, Thierry P. Carrel, Dominik Obrist - Heart Valve Society 1st Annual Meeting MAY 6-9, MONTE CARLO, MONACO, GRIMALDI FORUM
...so called hot spots, where activated platelets might aggregate and form a thrombus that can ultimately lead to leaflet blockage. It is the aim of this study to assess the hemodynamics in the pivoting area of the Triflo valve.
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Visit SourceIkechukwu U. Okafor, Arvind Santhanakrishnan, Brandon D. Chaffins, Lucia Mirabella, John N. Oshinski and Ajit P. Yoganathan - Journal of Cardiovascular Magnetic Resonance 2015, 17:51 doi:10.1186/s12968-015-0154-9
... A programmable piston pump (PPP; Vivitro Systems Inc., Victoria, Canada) was used to induce the LV wall motion by altering the pressure of the fluid in the space between the interior of acrylic chamber housing the LV model and the exterior of the LV model. ...
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Visit SourceClara Seaman, Andrew McNally, Stephen Biddle, Lauren Jankowski, Philippe Sucosky Presented in part at the 2013 Biomedical Engineering Society Conference, September 2013, Seattle, WA, and at the 2013 ASME Summer Bioengineering Conference, June 2013, Sunriver, OR, USA
The study aim was to develop a laboratory protocol for the fabrication of tissue valve models mimicking mild and moderate calcific stenosis, for future use in flow studies. ... near-physiologic hemodynamics. The flow loop was driven by a programmable piston pump (Vivitro), and included resistance and compliance units to mimic the characteristics of the systemic vascular tree (Fig. 3A). The system ...
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Visit SourceBarannyk O, Oshkai P. - J Biomech Eng. 2015 May; Epub 2015 Mar 5.
...he objective of this investigation is to establish a set of parameters, which are associated with abnormal flow patterns due to the flow through a prosthetic heart valve implanted in the patients that had certain types of valve diseases prior to the valve replacement.... ...By varying the aortic root geometry, while keeping the diameter of the orifice constant, it was possible to investigate corresponding changes in the levels of Reynolds shear stress and establish the possibility of platelet activation and, as a result of that, the formation of blood clots....
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Visit SourceA Falahatpisheh, G Pedrizzetti, A Kheradvar; Experiments in Fluids November 2014, 55:1848
... We used a heart-flow simulator consisting of a hydraulic pump system (Superpump system, VSI, SPS3891, Vivitro systems Inc., Victoria, BC, Canada) that operates based on a VSI Wave Generator VG2001 (Vivitro Systems Incorporated, Victoria, BC, Canada), as previously ...
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Visit SourceW.Lim; Journal of Biomechanics: 34, Issue 11; 1417-1427.
A two-dimensional particle image tracking velocimetry (PIV) system has been used to map the velocity vector fields and Reynolds stresses in the immediate downstream vicinity of a porcine bioprosthetic heart valve at the aortic root region in vitro under pulsatile flow conditions. Measurements were performed at five different time steps...
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Visit SourceSimcha Milo, Edmond Rambodb, Chaim Gutfingerc and Morteza Gharibb; European Journal of Cardio-Thoracic Surgery: 24, Issue 3; 364-370.
The goal of the present work was to create the closest possible in vitro fluid dynamic environment in which prosthetic mitral valves in the patients' hearts function, in order to demonstrate whether microbubbles are generated, and if yes, under what conditions and at which stage of the cardiac cycle...
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Visit SourceEuropean Journal of Vascular and Endovascular Surgery: 18, Issue 3; 191-200.
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Visit SourceAngiographic Quantification of Contrast Medium Washout from Cerebral Aneurysms after Stent Placement
Chander Sadasivana, Baruch B. Lieberc, Matthew J. Gounisc, Demetrius K. Lopese and L. N. Hopkinsb; American Journal of Neuroradiology: 23; 1214-1221.
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Visit SourceM L J Rose, G A Wright, T G Mackay, W Martin and D J Wheatley; Physiological Measurement: 18; 171-182; 1997.
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Visit SourceEdmond Rambod, Masoud Beizaie, Michael Shusser, Simcha Milo and Morteza Gharib; Annals of Biomedical Engineering: 27, Issue 6; 774-792; 1999.
This study was aimed at developing a physical model, supported by experimental observations, to describe the formation and growth of microbubbles seen in patients with mitral mechanical heart valves (MHV). This phenomenon, often referred to as high intensity transient signals (HITS), appears as bright, intense, high-velocity and persistent echoes detected by Doppler ultrasonography at the instant of closure.
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Visit SourceGrigioni, Mauro; Daniele, Carla; Del Gaudio, Costantino; Morbiducci, Umberto; Balducci, Antonio; D’Avenio, Giuseppe; Barbaro, Vincenzo; ASAIO Journal: 51, Issue 3; 176-183; 2005.
A three-dimensional, realistic model of an aortic mechanical heart valve and Valsalva sinuses was developed to predict, by means of a numerical time dependent simulation, the flow field during a fraction of the systolic period. The numeric simulation was performed upon a model of valve similar to a Carbomedics 27 mm placed in a physiologic aortic root shaped model,...
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Visit SourceKaminsky, Radoslav; Kallweit, Stephan; Weber, Hans J.; Simons, Antoine P.; Verdonck, Pascal; ASAIO Journal: 52, Issue 2; 4A; 2006.
Worldwide are performed approximately 225,000 heart valve operation procedures. Various heart valve types have different efficiency, beside others, mostly given by the quality of the flow in all regions across the valve. For the visualization of the flow we employed Stereo High Speed Particle Image Velocimetry (SHSPIV)...
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Visit SourceKheradvar, Arash; Kasalko, Jeff; Johnson, Derrick; Gharib, Morteza; ASAIO Journal: 52, Issue 1; 34-38; 2006.
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Visit SourceArash Kheradvar and Morteza Gharib; Annals of Biomedical Engineering: 35, Issue 12; 2050-2064; 2007.
Several studies have suggested that the mitral annulus displacement and velocity in early diastole can be used as indicators of diastolic performance.
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Visit SourceRadoslav Kaminsky, Stephan Kallweit, Hans-Joachim Weber, Tom Claessens, Krzysztof Jozwik, and Pascal Verdonck; Artificial Organs: 31, Issue 12; 869 – 879; 2007.
The number of candidates waiting for a heart valve replacement rises yearly. Even though there is a trend toward implantation of biological valves or reconstruction, the prosthetic heart valves (PHVs) are still commonly used for implantation or as a part of cardiac assist devices in many countries worldwide...
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Visit SourceKheradvar, Arash; Milano, Michele; Gharib, Morteza; ASAIO Journal: 53, Issue 1; 8-16; 2007.
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