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Teoh, S. H.; Lee, K. H.; Nugent, A. H.; Goh, K. S.; ASAIO Journal: 39, Issue 4; 1993.
To ascertain the stress magnitude at the stress concentration areas, in vitro strain measurements on a St. Vincent's mechanical heart valve were carried out in a pulse simulator.
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Visit SourceDavid K. Walker PhD**, Lawrence N. Scotten**: J Heart Valve Dis, Vol. 3 No. 5 Sep. 1994. **ViVitro Labs Founder
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Visit SourceM. Strüber, A. Campbell, G. Richard and J. Laas; European Journal of Cardio-Thoracic Surgery: 10, Issue 6; 422-427; 1996.
To determine the energy loss attributable to prosthetic valve size and design in double valve replacement, energy consumption of mitral valves (size #25 to #29), of two different designs (Bjork Shiley tilting disc and Carbomedics bileaflet valves), in combination with a small (#21) and large sized (#27) aortic prosthesis, were analyzed in a flow simulator.
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Visit SourceImportance of pressure recovery: Russell S. Heinrich, Arnold A. Fontaine, Randall Y. Grimes, Aniket Sidhaye, Serena Yan1, Kristin E. Moore, Robert A. Levine and Ajit P. Yoganathan; Annals of Biomedical Engineering: 24, Issue 6; 685-694; 1996.
Current methods for assessing the severity of aortic stenosis depend primarily on measures of maximum systolic pressure drop at the aortic valve orifice and related calculations such as valve area. It is becoming increasingly obvious, however, that the impact of the obstruction on the left ventricle is equally important in assessing its severity and could potentially be influenced by geometric factors of the valve, causing variable degrees of downstream pressure recovery...
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Visit SourceRichard H. Marcus, MBBCh; Russell S. Heinrich, BSE; James Bednarz, BS; Stephen Lupovitch, MD; Joseph Abruzzo, MD; Raphael Borok, MBBCh; Byron Vandenberg, MD; Richard E. Kerber, MD; William Piccione, MD; Ajit P. Yoganathan, PhD; Roberto M. Lang, MD; American Heart Association: 98; 866-872; 1998.
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Visit SourceA. A. Sakhaeimanesh; Y. S. Morsi; Journal of Medical Engineering & Technology: 23, Issue 2; 63 – 68; 1999.
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Visit SourceM. J. Thubrikar; G. G. Gong; I. E. Konstantinov; G. A. Selim; B. L. Fowler; F. Robicsek; Journal of Medical Engineering & Technology: 24, Issue 4; 173 – 180; 2000.
The function and longevity of the homograft aortic valve may be influenced by valve size and subcoronary implantation technique. Dynamic function and leaflet configuration of the porcine aortic valve were analysed first in its natural root in a left heart simulator using glycerol at 120/80 mm Hg pressure and 4 l min-1 Cardiac Output (C.O.)...
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Visit SourceYos S. Morsi; Journal of Artificial Organs: 3, Issue 2; 143-148; 2000.
In examining the hydrodynamic performance of artificial heart valves in vitro, experiments are carried out under either steady or pulsatile flow conditions. Steady flow experiments are simple to set up and analysis of the data is also simple; however, their validity and accuracy have been questioned...
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Visit SourceMakoto Arita, Kiyotaka Iwasaki, Mitsuo Umezu, Masanori Yoshida, Tetsuo Fujimoto, Hisayoshi Suma and Tadashi Isomura; Journal of Artificial Organs: 4, Issue 2; 131-137; 2001
The purpose of this study was to explore a valve selection criterion based on the impact force generated at valve closure, and to test a statistical mathematical model for comparing valve performance. The impact force generated at valve closure in the mitral position was measured continuously, using a load cell mounted in the left atrial section of a mock circulatory system...
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Visit SourceYos S. Morsi and Ali A. Sakhaeimanesh; Artificial Organs: 24, Issue 7; 564 – 574; 2001.
Thrombus formation and hemolysis have been linked to the dynamic flow characteristics of heart valve prostheses. To enhance our understanding of the flow characteristics past the aortic position of a Jellyfish (JF) valve in the left ventricle, in vitro laser Doppler anemometry (LDA) measurements were carried out under physiological pulsatile flow conditions...
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Visit SourceMano J. Thubrikar, PhDa, Francis Robicsek, MD, PhDa, Geoffrey G. Gong, MDa, Brett L. Fowler, BSa; The Annals of Thoracic Surgery: 71; S318-S322; 2001.
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Visit SourceNatascha Simon-Kupilik, MDa, Heinz Schima, PhDb, Leopold Huber, MEb, Reinhard Moidl, MDa, Gerhard Wipplingerb, Udo Losert, MDc, Ernst Wolner, MDa, Paul Simon, MD; The Annals of Thoracic Surgery: 73; 455-459; 2002.
Aortic root replacement for prosthetic aortic valve endocarditis with accompanying destruction of the aortic root is a well-established surgical intervention. However, there is still no consensus whether prosthetic material or allogeneic material should be used. Here we report on our experience with prosthetic composite and aortic allograft root replacement in such patients during a 10-year interval.
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Visit SourceDavid Paniagua, MD, José A. Condado, MD, José Besso, MD, Manuel Vélez, MD, Bruno Burger, MD, Salvatore Bibbo, MD, Douglas Cedeno, MD, Harry Acquatella, MD, Carlos Mejia, BA, Eduardo Induni, MD, and R. David Fish, MD; Texas Heart Institute Journal: 32, Issue 3; 393–398; 2005.
The transcatheter route is an emerging approach to treating valvular disease in high-risk patients. The 1st clinical antegrade transcatheter placement of an aortic valve prosthesis was reported in 2002. We describe the first retrograde transcatheter implantation of a new aortic valve prosthesis, in a 62-year-old man with inoperable calcific aortic stenosis and multiple severe comorbidities.
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Visit SourceCarsten J. Bellera, Michel R. Labrosseb, Francis Robicsek and Mano J. Thubrikar; Interactive Cardiovascular and Thoracic Surgery: 5; 526-530; 2006.
Our goal was to understand why it is difficult to achieve reliable valve competence after aortic valve-sparing surgery, and to propose quantitative data aimed at improving the outcome of the procedure. Valve-sparing procedures were performed in patients with dilated aortic roots and aortic regurgitation, and reproduced in physical models to explore what should be the restored dimensions of the aortic root and leaflets for valve sparing to be successful.
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Visit SourcePaulo C Santos, Luís R Gerola, Ivan Casagrande, Ênio Buffolo and David T Cheung; Asian Cardiovasc Thorac Ann ;15:413-417; 2007.
Calcification of glutaraldehyde-treated bioprosthetic heart valves is a major cause of long-term failure. We studied porcine aortic valves treated by the L-Hydro process and implanted into 14 juvenile sheep (group 1). Another 10 sheep were implanted with glutaraldehyde-treated porcine bioprostheses (group 2).
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Visit SourceQiang Wang, Fernando Jaramillo, Yasushi Kato, Leonard Pinchuk, and Richard T. Schoephoerster; J. Med. Devices 3, 011002, 2009.
Implantation methods for commercially available heart valve prostheses require open-chest access to the heart to perform the suturing process. In order to alleviate this complicated surgical implant technique, a “stent-valve” design was developed that will provide a less cumbersome implantation method and therefore a less invasive access to the heart...
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Visit SourceArash Kheradvar and Morteza Gharib; Annals of Biomedical Engineering: 37, Issue 1; 2009.
In the field of cardiology, the current ability to accurately detect diastolic dysfunction is unsatisfactory due to the lack of an effective diagnostic index. Isolated indexes obtained from echocardiography are all restricted to a certain aspect of ventricular diastolic function only, and individually cannot be regarded...
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Visit SourceAli N. Azadani, PhD, Nicolas Jaussaud, MD, Peter B. Matthews, BS, Liang Ge, PhD, T. Sloane Guy, MD, Timothy A.M. Chuter, MD, Elaine E. Tseng, MD.; Ann Thorac Surg 2009;88:1857-1863, Aug 11, 2009.
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Visit SourceTravis BR, Fowler BL, Robicsek F.; J Heart Valve Dis. (5):499-506; Sep 18, 2009.
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Visit SourceThomas E. Claiborne, Danny Bluestein, Richard T. Schoephoerster, The International Journal of Artificial Organs, Vol. 32, no. 5, pp. 262-271; 2009.
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