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H.Sodawalla, M.Alnajrani, J.Wells, et al., Journal of Biomedical Materials Research Part B: Applied Biomaterials114, no. 2 (2026): e70030
The ViVitro SuperPump enabled a physiologically relevant benchtop platform for evaluating treatment strategies for giant intracranial aneurysms using a rupture-prone 3D-printed model. In this study, researchers implemented a custom flow loop to compare flow diverter-only treatment, flow diverter combined with synthetic thrombus, and flow diverter with liquid embolic, while continuously monitoring intra-aneurysmal pressure and time to rupture. The results demonstrate that benchtop aneurysm testing provides a practical and repeatable approach for assessing treatment performance and mechanical stability under controlled physiological conditions, while underscoring the value of realistic in-vitro models for preclinical device evaluation
Other Products Cited: Customized Circulatory Loop Pulsatile Flow Simulation SuperPump
Visit SourceTymoshenko V, Suria AJ, Dimonte G, et al. Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery. 2026;0(0).
This study demonstrates how the ViVitro Labs SuperPump enables precise control of flow and stroke, providing the stable and clinically relevant hemodynamic conditions required to accurately quantify leakage. Automated versus manual suturing techniques in Bentall procedures were evaluated using an ex vivo passive beating heart model integrated into an advanced mock circulatory loop (MCL) platform. Twenty porcine hearts underwent Bentall surgery with either automated or manual suturing and were tested under progressively increasing aortic pressures using the ViVitro Labs SuperPump. The results revealed no significant difference in anastomotic leakage between the two techniques, even under hypertensive conditions. These findings indicate that automated suturing achieves comparable holding strength and hemostatic performance to manual methods, supporting its use in complex aortic root procedures.
Other Products Cited: Customized Circulatory Loop Pulsatile Flow Simulation SuperPump
Visit SourceMerhi, Y., Montero, K.L., Johansen, P. et al. npj Flex Electron 10, 31 (2026).
This work highlights how ViVitro systems enable realistic cardiovascular bench testing for next-generation bioelectronic devices, helping advance translational implant development. Using a ViVitro SuperPump to recreate physiologically relevant pulsatile left-heart conditions, this study evaluates a biodegradable PLLA piezoelectric sensor for real-time monitoring during aortic annuloplasty. The authors enhanced PLLA film performance through uniaxial stretching and thermal annealing, significantly increasing voltage output and enabling stable, pressure-correlated sensing in a ring-like prototype. Within the in-vitro setup, the sensor produced repeatable signals across clinically relevant pressure ranges, supporting its potential as a temporary smart implant.
Other Products Cited: Customized Circulatory Loop Customized circulatory systems Pulsatile Flow Simulation SuperPump
Visit SourceSibut-Pinote, Vincent; Reymon, Philippe; Cikirikcioglu, Mustafa; Bendjelid, Karim; Huber, Christoph. ASAIO Journal ():10.1097/MAT.0000000000002454, May 13, 2025.
Use of the ViVitro Labs Super Pump to build a complex mock circulatory loop to study the effect of VA-ECMO/IABP combination on the with systemic, coronary, cerebral, and renal circulation. In this study the ViVitro Labs system is used to improve the outcome of clinical procedures. "We used the same silicone circuit as in our previous publication (model ref T-S-N-009+; Elastrat, Geneva, Switzerland). To prevent the formation of air bubbles when testing at a heart rate of 100 bpm, and to improve the quality of aortic flow measurements, a rigid plastic grid was placed in the compliance reservoir tank. We used a pulsatile pump (Superpump; ViVitro Labs, Inc., Victoria, BC, Canada) to simulate cardiac function at the circuit inlet. Positioning the pump in line with the aortic root was the configuration with the fewest disturbances flow and pressure measurements (Figure 1)"
Other Products Cited: Customized Circulatory Loop Customized circulatory systems Pulsatile Flow Simulation SuperPump
Visit SourceKedwai, Baqir et al. JVS-Vascular Science, Volume 6, 100287
AAA sac management with persistent growth or endoleak in patient continue to be a challenge. This publication demonstrates the modularity of the ViVitro Labs Pulsatile Flow Pump in building advanced mock circulatory loops, and how the ViVitro Labs systems can be used to assess the impact of an embolization technique on the reduction of AAA sac volume and improve a procedure clinical outcome. "A Vivitro SuperPump (Victoria, BC, Canada) cardiac simulator was connected to both ends of a 30-gallon plastic basin using plastic tubing. The graft model construct was placed into the basin and securely attached proximally and distally to the plastic tubing with circumferential clamps. The basin was filled with water and gel beads for optimal acoustic conditions. Once the model was connected to the flow circuit, water was pumped through the system at 70 beats per minute with an average flow rate of 3.5 L/min."
Other Products Cited: Customized Circulatory Loop Customized circulatory systems Endovascular Simulator Stent and Stent/Graft SuperPump
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