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M Ismail, F Kabinejadian, YN Nguyen, E Tay, S Kim… - Artificial Organs, 2015 Article first published online: 29 APR 2015 DOI: 10.1111/aor.12457
Severe tricuspid regurgitation (TR) is life-threatening but is often undertreated. Many patients with severe TR are denied heart valve replacement surgery because their old age or comorbidities predispose them to a higher risk of surgical complications associated with open-heart surgery. ... by 19% as an initial study. The silicone atrium was incorporated into a pulsatile flow loop that was driven by a wave-generating piston pump (SuperPump AR series, ViVitro Labs Inc., Victoria, BC, Canada). The flow rate in the ...
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Visit SourceZbigniew Trawińskia, Janusz Wójcika, Andrzej Nowickia, Robert Olszewskib, Andrzej Balcerzaka, Emilia Frankowskac, Arkadiusz Zegadłoc, Paweł Rydzyńskic -Biocybernetics and Biomedical Engineering 27 March 2015
The main aim of this study was to verify the suitability of the hydrogel sonographic model of the left ventricle (LV) in the computed tomography (CT) environment and echocardiography and compare the radial strain calculations obtained by two different techniques: the speckle tracking ultrasonography and the multislices computed tomography (MSCT). ... equal to 0.28 dB/cm (at 2.95 MHz). Our model of the LV was driven by a computer-controlled hydraulic piston Super-Pump (Vivitro Inc., Canada) with adjustable fluid volumes and various loads. During a cycle of the pump, the ...
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Visit SourceKonduri S, Xing Y, Warnock JN, He Z, Yoganathan AP. - Ann Biomed Eng. 2005 Sep;33(9):1158-66.
The aortic valve functions in a complex mechanical environment which leads to force-dependent cellular and tissue responses. Characterization of these responses provides a fundamental understanding of valve pathogenesis. The aim of this work was to study the biological characteristics of native porcine aortic valves cultured in an ex vivo pulsatile organ culture system capable of maintaining physiological pressures (120/80 mmHg) and cardiac output (4.2 l/min).
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Visit SourceNicolas Brugger, MD, , Kerstin Wustmann, MD, Michael Hürzeler, BS, Andreas Wahl, MD, Stefano F. de Marchi, MD, Hélène Steck, RN, Fabian Zürcher, MD, Christian Seiler, MD, The American Journal of Cardiology Available online 3 February 2015
The aim of our study was, to evaluate 3-D color Doppler proximal isovelocity surface area (PISA) as a tool for quantitative assessment of mitral regurgitation (MR) against in vitro and in vivo reference methods. A customized 3-D PISA software was validated in vitro against a flowmeter MR phantom. Sixty consecutive patients, with ≥mild MR of any etiology, were recruited and the regurgitant volume (RVol) was measured by 2-D PISA, 3-D peak PISA, 3-D integrated PISA, using transthoracic (TTE) and transesophageal echocardiography (TEE).
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Visit SourceE Frankowska, Z Trawi; Poster No.: C-0473 Congress: ECR 2014 Type: Scientific Exhibit
... Model of the LV was made from solution of POLY(VINYL ALCOHOL). Pulsatile filling of the LV phantom was driven by automatic and computer controlled hydraulic piston pump (Vivitro Inc., Canada) with stroke volume of 20 ml and the frequency of 60 impactions per minute. ...
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Visit SourceA Falahatpisheh, G Pedrizzetti, A Kheradvar; Experiments in Fluids November 2014, 55:1848
... We used a heart-flow simulator consisting of a hydraulic pump system (Superpump system, VSI, SPS3891, Vivitro systems Inc., Victoria, BC, Canada) that operates based on a VSI Wave Generator VG2001 (Vivitro Systems Incorporated, Victoria, BC, Canada), as previously ...
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Visit SourceZ Trawiński, J Wójcik, A Nowicki, A Balcerzak…
... Our model of the LV was driven by the computer-controlled hydraulic piston Super-Pump (Vivitro Inc., Canada) with adjustable fluid volumes. ... The data were reconstructed every 10% of the R-to-R interval of the ECG signal produced by the Vivitro SuperPump control device. ...
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Visit SourceGeorge P. Chatzimavroudis, PhD, John N. Oshinski, PhD, Roderic I. Pettigrew, MD, PhD, Peter G. Walker, PhD, Robert H. Franch, MD, Ajit P. Yoganathan, PhD; Journal of Magnetic Resonance Imaging: 8, Issue 3; 577 – 582.
Reliable diagnosis and quantification of mitral regurgitation are important for patient management and for optimizing the time for surgery. Previous methods have often provided suboptimal results. The aim of this in vitro study was to evaluate MR phase-velocity mapping in quantifying the mitral regurgitant volume (MRV) using a control volume (CV) method.
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Visit SourceSimcha Milo, Edmond Rambodb, Chaim Gutfingerc and Morteza Gharibb; European Journal of Cardio-Thoracic Surgery: 24, Issue 3; 364-370.
The goal of the present work was to create the closest possible in vitro fluid dynamic environment in which prosthetic mitral valves in the patients' hearts function, in order to demonstrate whether microbubbles are generated, and if yes, under what conditions and at which stage of the cardiac cycle...
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Visit SourcePoulsen, J.K. Kim, W.Y; IEEE Transactions on Biomedical Engineering: 43, Issue 6; 589-599.
In this paper we show that by scanning at points on the surface of a sphere that the normal angle correction used in pulsed Doppler flow measurements is no longer necessary.
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Visit SourceG. Tansley, S. Vidakovic, and J. Reizes; Artificial Organs: 24, Issue 6; 483 – 487.
The VentrAssist pump has no shaft or seal, and the device is unique in design because the rotor is suspended passively by hydrodynamic forces, and urging is accomplished by an integrated direct current motor rotor that also acts as the pump impeller. This device has led to many challenges in its fluidic design...
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Visit SourceDaniel Zimpfer MDa, Heinz Schima PhDb, Martin Czerny MDa, Marie-Theres Kasimir MDa, Sigrid Sandner MDa, Gernot Seebacher MDa, Udo Losert PhDc, Paul Simon MDa, Michael Grimm MDa, Ernst Wolner MD, PhDa and Marek Ehrlich MD; The Annals of Thoracic Surgery: 85, Issue 2; 470-473.
BACKGROUND: This study assessed the feasibility of stent graft treatment of ascending aortic dissections in a porcine in vitro model. METHODS: The entire thoracic aortic aorta including the supraaortic branches was harvested from 12 adult pigs and an intimal tear was artificially created. ...
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Visit SourceNwosuh, I.A. Roberts, D. Kosiniski, S. Ciampa, S. Thomas, G.A.; Bioengineering Conference, 2005. Proceedings of the IEEE 31st Annual Northeast; 20- 21.
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Visit SourceJ.Mascherbauer, R.Rosenhek, B.Bittner, J.Binder, P.Simon, G.Maurer, H.Schima, H.Baumgartner; Journal of the American Society of Echocardiography: 18, Issue 10; 999-1006.
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Visit SourceEuropean Journal of Vascular and Endovascular Surgery: 18, Issue 3; 191-200.
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Visit SourceC. C. M. Rindt, A. A. van Steenhoven, J. D. Janssen a and G. Vossers; Journal of Fluid Mechanics: 226; 445-474; 1991.
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Visit SourceOsamu Kawaguchi, MD, Yoichi Goto, MD, Shiho Futaki, MD, Yuichi Ohgoshi, MD, Hitoshi Yaku, MD, Hiroyuki Suga, MDa; The Journal of Thoracic and Cardiovascular Surgery: 107; 850-859; 1994.
The purpose of this study was to determine the role of ventricular size or contractility in the effectiveness of dynamic cardiac compression in terms of the pressure-volume relationship and myocardial oxygen consumption. In 10 isolated cross-circulated dog hearts, the ventricle was directly compressed during systole.
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Visit SourceImportance of pressure recovery: Russell S. Heinrich, Arnold A. Fontaine, Randall Y. Grimes, Aniket Sidhaye, Serena Yan1, Kristin E. Moore, Robert A. Levine and Ajit P. Yoganathan; Annals of Biomedical Engineering: 24, Issue 6; 685-694; 1996.
Current methods for assessing the severity of aortic stenosis depend primarily on measures of maximum systolic pressure drop at the aortic valve orifice and related calculations such as valve area. It is becoming increasingly obvious, however, that the impact of the obstruction on the left ventricle is equally important in assessing its severity and could potentially be influenced by geometric factors of the valve, causing variable degrees of downstream pressure recovery...
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Visit SourceGeorge P. Chatzimavroudis, Peter G. Walker, John N. Oshinski, Robert H. Franch, Roderic I. Pettigrew and Ajit P. Yoganathan; Annals of Biomedical Engineering: 25, Issue 4; 644-652; 1997.
Although several methods have been used clinically to evaluate the severity of aortic regurgitation, there is no purely quantitative approach for aortic regurgitant volume (ARV) measurements. Magnetic resonance phase velocity mapping can be used to quantify the ARV, with a single imaging slice in the ascending aorta, from through-slice velocity measurements.
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Visit SourceOsamu Kawaguchi, MDa, Yoichi Goto, MDb, Yuichi Ohgoshi, MDb, Hitoshi Yaku, MDb, Mitsuya Murase, MDa, Hiroyuki Suga, MDc; The Journal of Thoracic and Cardiovascular Surgery: 113; 923-931; 1997.
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